RPS25 and SC5D

Data Source:
BioGRID (two hybrid)

		RPS25	SC5D
Description		ribosomal protein S25	sterol-C5-desaturase
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytosol Ribosome Postsynaptic Density Small Ribosomal Subunit Cytosolic Small Ribosomal Subunit Extracellular Exosome	Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane
	Molecular Function	RNA Binding Structural Constituent Of Ribosome Protein Binding	C-5 Sterol Desaturase Activity Iron Ion Binding Oxidoreductase Activity
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay RRNA Processing Translation Translational Initiation SRP-dependent Cotranslational Protein Targeting To Membrane Viral Transcription Ribosomal Small Subunit Biogenesis	Lipid Metabolic Process Sterol Biosynthetic Process Cholesterol Biosynthetic Process Via Desmosterol Cholesterol Biosynthetic Process Via Lathosterol Regulation Of Cholesterol Biosynthetic Process
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	Activation of gene expression by SREBF (SREBP) Cholesterol biosynthesis via desmosterol Cholesterol biosynthesis via lathosterol
Drugs
Diseases
GWAS
Interacting Genes		13 interacting genes: APP DUX4 HAP1 HMBOX1 HOMEZ NKAPD1 PTEN SGSM2 STAC3 THAP1 TSPYL2 UPF2 ZBTB14
Entrez ID		6230	6309
HPRD ID		01593	09078
Ensembl ID		ENSG00000118181	ENSG00000109929
Uniprot IDs		P62851	A0A024R3G4 O75845
PDB IDs		4UG0 4V6X 5A2Q 5AJ0 5FLX 5LKS 5OA3 5T2C 5VYC 6EK0 6FEC 6G18 6G4S 6G4W 6G51 6G53 6G5H 6G5I 6IP5 6IP6 6IP8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6XA1 6Y0G 6Y2L 6Y57 6YBS 6Z6L 6Z6M 6Z6N 6ZLW 6ZM7 6ZME 6ZMI 6ZMO 6ZMT 6ZMW 6ZN5 6ZOJ 6ZOL 6ZON 6ZP4 6ZVH 6ZVJ 7A09 7K5I
Enriched GO Terms of Interacting Partners?
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