RPS4Y1 and TMPRSS15

Data Source:
BioGRID (affinity chromatography technology)

		RPS4Y1	TMPRSS15
Description		ribosomal protein S4 Y-linked 1	transmembrane serine protease 15
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Polysome Membrane Cytosolic Small Ribosomal Subunit	Brush Border Membrane Integral Component Of Membrane
	Molecular Function	RNA Binding Structural Constituent Of Ribosome Protein Binding RRNA Binding	Serine-type Endopeptidase Activity Scavenger Receptor Activity Protein Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation SRP-dependent Cotranslational Protein Targeting To Membrane Multicellular Organism Development Viral Transcription	Proteolysis Endocytosis
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases			Enterokinase deficiency
GWAS			Asthma ( 29273806) Bulimia nervosa ( 23568457) Nucleus accumbens volume in trauma-exposed individuals ( 29187748)
Interacting Genes		3 interacting genes: CALM1 CLK1 MEOX2	1 interacting genes: SPINK1
Entrez ID		6192	5651
HPRD ID		15963	05972
Ensembl ID		ENSG00000129824	ENSG00000154646
Uniprot IDs		P22090	P98073
PDB IDs		5AJ0 5FLX 6OLG 6OLZ	4DGJ 6ZOV
Enriched GO Terms of Interacting Partners?
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