TGIF2 and PLS3

Data Source:
BioGRID (pull down, affinity chromatography technology)

		TGIF2	PLS3
Description		TGFB induced factor homeobox 2	plastin 3
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Centrosome	Cytoplasm Cytosol Actin Filament Plasma Membrane Actin Filament Bundle
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Sequence-specific Double-stranded DNA Binding	Calcium Ion Binding Actin Filament Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Regulation Of Gastrulation Nodal Signaling Pathway Positive Regulation Of Neuron Differentiation Retina Development In Camera-type Eye	Actin Filament Bundle Assembly Actin Filament Network Formation Bone Development
Pathways		Downregulation of SMAD2/3:SMAD4 transcriptional activity SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
Drugs
Diseases
GWAS			Gestational age at birth (maternal effect) ( 28877031) Mean platelet volume ( 32888494) Platelet count ( 32888494) Platelet distribution width ( 32888494) Preterm birth (maternal effect) ( 28877031)
Interacting Genes		5 interacting genes: FBXO7 HDAC1 RBBP8 SMAD3 TARBP2	2 interacting genes: APP ATXN2
Entrez ID		60436	5358
HPRD ID		06293	02133
Ensembl ID		ENSG00000118707	ENSG00000102024
Uniprot IDs		Q9GZN2	B4DPW9 P13797
PDB IDs			1AOA 1WJO
Enriched GO Terms of Interacting Partners?
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