RFX5 and TUBD1

Data Source:
BioGRID (affinity chromatography technology)

		RFX5	TUBD1
Description		regulatory factor X5	tubulin delta 1
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin RNA Polymerase II Transcription Regulator Complex	Nucleoplasm Cytoplasm Centriole Cytosol Microtubule Cilium
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding	GTPase Activity Structural Constituent Of Cytoskeleton GTP Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II	Microtubule Cytoskeleton Organization Mitotic Cell Cycle Multicellular Organism Development Cell Projection Organization Positive Regulation Of Smoothened Signaling Pathway
Pathways
Drugs			Vinblastine
Diseases		Bare lymphocyte syndrome (BLS) type2 Combined immunodeficiencies (CIDs), including the following nine diseases: X-linked hyper IgM syndrome; CD40 deficiency hyper IgM syndrome; Purine nucleoside phosphorylase (PNP) deficiency; Omenn syndrome; MHC deficiency (HLA-class I); MHC deficiency (HLA-class II); Zap-70 deficiency; p56 Lck deficiency; CD8 deficiency
GWAS		Body mass index ( 26426971)	C-reactive protein levels ( 30388399) Chronotype ( 30696823) Crohn's disease ( 28067908) Eosinophil counts ( 32888494) Eosinophil percentage of granulocytes ( 27863252) Hemoglobin levels ( 32327693) Inflammatory bowel disease ( 23128233) Mean reticulocyte volume ( 32888494) Monocyte count ( 29403010) Obesity-related traits ( 23251661) Red blood cell count ( 32888494) Red cell distribution width ( 32888494 27863252 28957414) Systolic blood pressure ( 30578418)
Interacting Genes		5 interacting genes: APP CIITA HDAC2 RFXANK RFXAP	1 interacting genes: TOP1
Entrez ID		5993	51174
HPRD ID		03517	06297
Ensembl ID		ENSG00000143390	ENSG00000108423
Uniprot IDs		P48382	Q9UJT1
PDB IDs		2KW3 3V30
Enriched GO Terms of Interacting Partners?
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