CARD18 and DYNC2H1

Data Source:
BioGRID (affinity chromatography technology)

		CARD18	DYNC2H1
Description		caspase recruitment domain family member 18	dynein cytoplasmic 2 heavy chain 1
Image
GO Annotations	Cellular Component	Protein-containing Complex	Golgi Apparatus Cytoplasmic Dynein Complex Microtubule Plasma Membrane Cilium Axoneme Dynein Complex Motile Cilium Apical Part Of Cell Extracellular Exosome Ciliary Tip
	Molecular Function	Cysteine-type Endopeptidase Inhibitor Activity Protein Binding CARD Domain Binding Caspase Binding	Motor Activity Protein Binding ATP Binding ATP-dependent Microtubule Motor Activity, Minus-end-directed Dynein Intermediate Chain Binding Dynein Light Intermediate Chain Binding
	Biological Process	Inflammatory Response Negative Regulation Of Protein Binding Negative Regulation Of Interleukin-1 Beta Production Regulation Of Apoptotic Process Inhibition Of Cysteine-type Endopeptidase Activity	Kidney Development Microtubule-based Movement Golgi Organization Determination Of Left/right Symmetry Dorsal/ventral Pattern Formation Protein Processing Spinal Cord Motor Neuron Differentiation Embryonic Limb Morphogenesis Forebrain Development Intraciliary Retrograde Transport Intraciliary Transport Involved In Cilium Assembly Positive Regulation Of Smoothened Signaling Pathway Cilium Assembly Coronary Vasculature Development Protein Localization To Cilium Non-motile Cilium Assembly
Pathways			Hedgehog 'off' state Intraflagellar transport
Drugs
Diseases			Short rib-polydactyly syndrome Asphyxiating thoracic dystrophy; Jeune syndrome
GWAS			Adult body size ( 32376654) Coronary artery disease ( 32469254 30104761 33020668) Diisocyanate-induced asthma ( 25918132) Response to lurasidone in schizophrenia ( 29730043) Small-cell lung cancer (survival) ( 21118971) Spine bone mineral density and alcohol drinking ( 28012008) Toenail selenium levels ( 25343990) Tuberculosis ( 24057671)
Interacting Genes		2 interacting genes: CARD17 CARD8	3 interacting genes: DYNC2LI1 MTNR1B PAXIP1
Entrez ID		59082	79659
HPRD ID		16099	10344
Ensembl ID		ENSG00000255501	ENSG00000187240
Uniprot IDs		P57730	Q8NCM8
PDB IDs		1DGN	4RH7
Enriched GO Terms of Interacting Partners?
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