OVOL2 and KIZ

Data Source:
HPRD (in vivo)

		OVOL2	KIZ
Description		ovo like zinc finger 2	kizuna centrosomal protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Cytoplasm Centrosome Cell Projection
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Chromatin Binding Protein Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	Protein Binding Protein Kinase Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Angiogenesis Neural Crest Cell Migration Neural Fold Formation Heart Looping Regulation Of Transcription By RNA Polymerase II Epidermal Cell Differentiation Dorsal/ventral Pattern Formation Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Negative Regulation Of Epithelial To Mesenchymal Transition Regulation Of Keratinocyte Proliferation Positive Regulation Of Keratinocyte Differentiation Positive Regulation Of Transcription By RNA Polymerase II Embryonic Digestive Tract Morphogenesis Endocardium Formation Heart Trabecula Formation Regulation Of SMAD Protein Signal Transduction Labyrinthine Layer Blood Vessel Development Cellular Response To Transforming Growth Factor Beta Stimulus Negative Regulation Of Stem Cell Proliferation	Spindle Organization
Pathways
Drugs
Diseases
GWAS		Low density lipoprotein cholesterol levels ( 32154731) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Nicotine dependence symptom count ( 25555482) Red blood cell count ( 32888494)	anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder ( 30804558) Height ( 31562340)
Interacting Genes		2 interacting genes: PARP1 ZNF526	3 interacting genes: MEOX2 TACC3 TFIP11
Entrez ID		58495	55857
HPRD ID		15780	12760
Ensembl ID		ENSG00000125850	ENSG00000088970
Uniprot IDs		Q9BRP0	A0A087X251 Q2M2Z5
PDB IDs
Enriched GO Terms of Interacting Partners?
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