PXMP2 and IMPDH2

Data Source:
BioGRID (affinity chromatography technology)

		PXMP2	IMPDH2
Description		peroxisomal membrane protein 2	inosine monophosphate dehydrogenase 2
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Peroxisomal Membrane Membrane Integral Component Of Membrane Protein-containing Complex	Extracellular Region Nucleus Cytoplasm Peroxisomal Membrane Cytosol Membrane Secretory Granule Lumen Extracellular Exosome Ficolin-1-rich Granule Lumen
	Molecular Function	Protein Binding	Nucleotide Binding DNA Binding RNA Binding IMP Dehydrogenase Activity Protein Binding Metal Ion Binding
	Biological Process	Biological_process	GMP Biosynthetic Process GTP Biosynthetic Process Circadian Rhythm Purine Ribonucleoside Monophosphate Biosynthetic Process Neutrophil Degranulation
Pathways		Glyoxylate metabolism and glycine degradation Class I peroxisomal membrane protein import	Neutrophil degranulation Purine ribonucleoside monophosphate biosynthesis Potential therapeutics for SARS
Drugs			NADH Mycophenolate mofetil Ribavirin Mycophenolic acid Mercaptopurine Selenazole-4-carboxyamide-adenine dinucleotide 6-Chloropurine Riboside, 5'-Monophosphate Inosinic Acid VX-148
Diseases
GWAS		Immature fraction of reticulocytes ( 32888494) Mean corpuscular hemoglobin ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494)	Blood protein levels ( 28240269) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 28067908)
Interacting Genes		2 interacting genes: KRT40 SIVA1	15 interacting genes: AGR2 AKT1 ANKRD9 APIP CLK1 CPLANE2 IL1F10 IMPDH1 PIAS4 POU6F2 STAT3 SUMO2 SUMO4 TRAF2 UBQLN4
Entrez ID		5827	3615
HPRD ID		10176	00895
Ensembl ID		ENSG00000176894	ENSG00000178035
Uniprot IDs		Q9NR77	A0A384N6C2 P12268
PDB IDs			1B3O 1NF7 1NFB 6I0M 6I0O 6U8E 6U8N 6U8R 6U8S 6U9O 6UA2 6UA4 6UA5 6UAJ 6UC2 6UDO 6UDP 6UDQ
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?