SLC4A5 and ALMS1

Data Source:
BioGRID (affinity chromatography technology)

		SLC4A5	ALMS1
Description		solute carrier family 4 member 5	ALMS1 centrosome and basal body associated protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Apical Plasma Membrane	Spindle Pole Centrosome Centriole Cytosol Cilium
	Molecular Function	Inorganic Anion Exchanger Activity Sodium:bicarbonate Symporter Activity Anion:anion Antiporter Activity Transmembrane Transporter Activity	Molecular_function Protein Binding Microtubule Binding
	Biological Process	Epithelial Cell Development Renal System Process Regulation Of Systemic Arterial Blood Pressure Regulation Of Gene Expression Inorganic Anion Transport Bicarbonate Transport Cerebrospinal Fluid Secretion Sodium Ion Transmembrane Transport Mitochondrion Distribution Ion Homeostasis Regulation Of Intracellular PH Transmembrane Transport Retina Development In Camera-type Eye Anion Transmembrane Transport	G2/M Transition Of Mitotic Cell Cycle Regulation Of G2/M Transition Of Mitotic Cell Cycle Endosomal Transport Regulation Of Centriole Replication Regulation Of Stress Fiber Assembly Ciliary Basal Body-plasma Membrane Docking Positive Regulation Of Cold-induced Thermogenesis
Pathways		Bicarbonate transporters	Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases			Alstrom syndrome (AS)
GWAS		Immune reponse to smallpox (secreted TNF-alpha) ( 22610502) Post-traumatic stress disorder (asjusted for relatedness) ( 23726511) Refractive error ( 32231278)	Age at voice drop ( 27182965) Blood metabolite levels ( 26401656) Chronic kidney disease ( 20383146) Creatinine levels ( 20383145) Estimated glomerular filtration rate ( 31015462 31451708) Estimated glomerular filtration rate in non-diabetics ( 31451708) Glomerular filtration rate ( 27588450) Glomerular filtration rate (creatinine) ( 26831199) Glomerular filtration rate in non diabetics (creatinine) ( 26831199) Intelligence (MTAG) ( 29326435) Menarche (age at onset) ( 27182965) Metabolite levels ( 21931564) Metabolite levels (X-11787) ( 23934736) Serum metabolite levels ( 23093944) Urinary metabolite levels in chronic kidney disease ( 29545352) Urinary metabolite ratios in chronic kidney disease ( 29545352) Urinary metabolites (H-NMR features) ( 24586186)
Interacting Genes			3 interacting genes: GTF2IRD1 LIG4 MEGF10
Entrez ID		57835	7840
HPRD ID		08420	06023
Ensembl ID		ENSG00000188687	ENSG00000116127
Uniprot IDs		Q9BY07	Q8TCU4
PDB IDs
Enriched GO Terms of Interacting Partners?
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