TMEM181 and TAGAP

Data Source:
HPRD (in vivo)

		TMEM181	TAGAP
Description		transmembrane protein 181	T cell activation RhoGTPase activating protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Cytosol
	Molecular Function	Toxic Substance Binding	Guanyl-nucleotide Exchange Factor Activity GTPase Activator Activity Protein Binding
	Biological Process	Pathogenesis	Signal Transduction Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction
Pathways			Rho GTPase cycle
Drugs
Diseases
GWAS		Glaucoma ( 31959993) Glaucoma (primary open-angle) ( 29891935) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Intraocular pressure ( 29785010 31959993)	Autoimmune traits (pleiotropy) ( 30572963) Bladder cancer (smoking interaction) ( 24662972) Celiac disease ( 22057235 20190752 25920553 24999842 30572963 18311140) Celiac disease and Rheumatoid arthritis ( 26546613) Crohn's disease ( 21102463 23128233) Crohn's disease and celiac disease ( 21298027) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Lipoprotein (a) - cholesterol levels ( 25575512) Lipoprotein (a) levels ( 26377243) Multiple sclerosis ( 31604244 22190364 24076602 21833088) Psoriasis ( 23143594) Rheumatoid arthritis ( 30423114 24390342) Rheumatoid arthritis (ACPA-positive) ( 23143596 24532676) Systemic lupus erythematosus ( 28714469)
Interacting Genes			1 interacting genes: HSF2BP
Entrez ID		57583	117289
HPRD ID		19623	18143
Ensembl ID		ENSG00000146433	ENSG00000164691
Uniprot IDs		Q9P2C4	Q8N103
PDB IDs
Enriched GO Terms of Interacting Partners?
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