MICAL3 and ZDHHC8

Data Source:
BioGRID (affinity chromatography technology)

		MICAL3	ZDHHC8
Description		microtubule associated monooxygenase, calponin and LIM domain containing 3	zinc finger DHHC-type palmitoyltransferase 8
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Spindle Cytosol Plasma Membrane Cell Cortex Cell Projection Intercellular Bridge Flemming Body	Golgi Membrane Golgi Apparatus Cytosol Integral Component Of Membrane Mitochondrial Membrane
	Molecular Function	Actin Binding Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, NAD(P)H As One Donor, And Incorporation Of One Atom Of Oxygen Metal Ion Binding FAD Binding	Palmitoyltransferase Activity Protein-cysteine S-palmitoyltransferase Activity
	Biological Process	Exocytosis Cytoskeleton Organization Cell Cycle Actin Filament Depolymerization Cell Division	Locomotory Behavior Positive Regulation Of Cholesterol Efflux Protein Phosphopantetheinylation Peptidyl-L-cysteine S-palmitoylation Protein Palmitoylation High-density Lipoprotein Particle Assembly Positive Regulation Of Protein Localization To Plasma Membrane
Pathways			HDL assembly
Drugs
Diseases
GWAS		Body mass index ( 28552196) Chronic obstructive pulmonary disease ( 30804561) Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444) Coronary artery calcified atherosclerotic plaque score in type 2 diabetes ( 29221444) Diastolic blood pressure ( 27841878) Diisocyanate-induced asthma ( 25918132) FEV1 ( 30804560) Liver enzyme levels (gamma-glutamyl transferase) ( 22001757) Lung function (FEV1) ( 28166213) Lung function (FEV1/FVC) ( 30804560) Lung function (FVC) ( 30804560) Lung function (low FEV1 vs high FEV1) ( 26423011) Lung function in never smokers (low FEV1 vs high FEV1) ( 26423011) Lymphocyte counts ( 32888494) Monocyte count ( 32888494) Pancreatic cancer ( 29422604) Peak expiratory flow ( 30804560) Presence of antiphospholipid antibodies ( 23509613) Response to hepatitis B vaccine ( 29534301) Triglyceride levels x short total sleep time interaction (2df test) ( 31719535) White blood cell count ( 32888494)
Interacting Genes		1 interacting genes: RAB1B
Entrez ID		57553	29801
HPRD ID		19352	12298
Ensembl ID		ENSG00000243156	ENSG00000099904
Uniprot IDs		Q7RTP6	Q9ULC8
PDB IDs		2D88 5SZG 6ICI
Enriched GO Terms of Interacting Partners?
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