ARID1B and PLEKHG1

Data Source:
HPRD (in vivo, in vitro)

		ARID1B	PLEKHG1
Description		AT-rich interaction domain 1B	pleckstrin homology and RhoGEF domain containing G1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol Plasma Membrane SWI/SNF Complex Brahma Complex NBAF Complex	Nucleoplasm
	Molecular Function	DNA Binding Transcription Coactivator Activity Protein Binding Nucleosome Binding
	Biological Process	Response To Ischemia Regulation Of Transcription By RNA Polymerase II Nervous System Development ATP-dependent Chromatin Remodeling Positive Regulation Of Transcription, DNA-templated Chromatin-mediated Maintenance Of Transcription Cellular Response To Angiotensin	Regulation Of Catalytic Activity
Pathways		RMTs methylate histone arginines RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406) Alzheimer's disease biomarkers ( 23419831) Calcium levels ( 24068962) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Heel bone mineral density ( 30598549) Hematocrit ( 32888494) Hemoglobin levels ( 32327693) Iris color (b* coordinate) ( 30895295) Lipoprotein (a) levels ( 26377243) Low density lipoprotein cholesterol levels ( 30498476) Multiple system atrophy (pathologically confirmed) ( 27629089) Pancreatic cancer ( 22158540) Psychosis proneness (perceptual aberration scale and revised physical anhedonia scale) ( 28525603) Pulse pressure ( 27841878) Red blood cell count ( 32888494) Sensory disturbances after bilateral sagittal split ramus osteotomy ( 23834954) Type 2 diabetes ( 29621232) Vein graft stenosis in coronary artery bypass grafting ( 25881214) Western dietary pattern ( 28644415)	Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653) Alcohol and nicotine co-dependence ( 22488850) Alzheimer's disease (cognitive decline) ( 23535033) Blood pressure ( 23972371) Blood pressure traits (multi-trait analysis) ( 28498854) Cadmium levels ( 26025379) Coronary artery disease ( 29212778) Diastolic blood pressure ( 27841878 28739976 27618452 28498854) Diastolic blood pressure (cigarette smoking interaction) ( 29455858) Diastolic blood pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962) Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962) Hematocrit ( 32888494) Malaria ( 31844061) Mean arterial pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962) Mean arterial pressure x alcohol consumption interaction (2df test) ( 29912962) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Medication use (calcium channel blockers) ( 31015401) Medication use (diuretics) ( 31015401) Obesity-related traits ( 23251661) Panic disorder ( 19165232) Periventricular white matter hyperintensities ( 32517579) Red cell distribution width ( 32888494) Systolic blood pressure ( 27841878 28739976 27618452 28498854 30578418) Systolic blood pressure (cigarette smoking interaction) ( 29455858) Systolic blood pressure in sickle cell anemia ( 24058526) Systolic blood pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962) Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962) White matter hyperintensities ( 32358547) White matter hyperintensity volume ( 30659137)
Interacting Genes		7 interacting genes: CUL2 ENO1 H2BC21 PYGM SMAD9 SMARCA2 SMARCA4	2 interacting genes: CDC42 RAC1
Entrez ID		57492	57480
HPRD ID		10660	18850
Ensembl ID		ENSG00000049618	ENSG00000120278
Uniprot IDs		Q8NFD5	Q5JYA6 Q9ULL1
PDB IDs		2CXY 2EH9
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?