SLC12A5 and MYL9

Data Source:
BioGRID (biochemical)

		SLC12A5	MYL9
Description		solute carrier family 12 member 5	myosin light chain 9
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane Neuron Projection Neuronal Cell Body Synapse Cell Periphery	Stress Fiber Cytosol Muscle Myosin Complex Z Disc
	Molecular Function	Chloride Transmembrane Transporter Activity Potassium:chloride Symporter Activity	Calcium Ion Binding Structural Constituent Of Muscle Myosin Heavy Chain Binding
	Biological Process	Ion Transport Cellular Ion Homeostasis Cell Volume Homeostasis Hypotonic Response Chemical Synaptic Transmission Learning Cellular Chloride Ion Homeostasis Multicellular Organism Growth Thermosensory Behavior Response To Drug Chloride Ion Homeostasis Potassium Ion Homeostasis Dendritic Spine Development Chloride Transmembrane Transport Potassium Ion Import Across Plasma Membrane	Muscle Contraction Regulation Of Muscle Contraction Regulation Of Megakaryocyte Differentiation Platelet Aggregation
Pathways		Cation-coupled Chloride cotransporters	EPHA-mediated growth cone collapse Sema4D induced cell migration and growth-cone collapse Smooth Muscle Contraction RHO GTPases activate PKNs RHO GTPases activate CIT RHO GTPases Activate ROCKs RHO GTPases activate PAKs RHO GTPases activate PAKs RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
Drugs		Potassium chloride Bumetanide
Diseases
GWAS		Chronotype ( 30696823) Crohn's disease ( 28067908) General risk tolerance (MTAG) ( 30643258) Inflammatory bowel disease ( 28067908) Reticulocyte count ( 32888494) Systemic sclerosis ( 29293537) Triglyceride levels ( 32154731)
Interacting Genes		2 interacting genes: CCR4 F2RL1	6 interacting genes: CDC42BPA HSPB1 LRRK2 MSGN1 MYH9 TXN2
Entrez ID		57468	10398
HPRD ID		09469	17619
Ensembl ID		ENSG00000124140	ENSG00000101335
Uniprot IDs		Q9H2X9	A0A384NY64 P24844
PDB IDs		6M23
Enriched GO Terms of Interacting Partners?
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