PBXIP1 and TRAF7

Data Source:
BioGRID (affinity chromatography technology)

		PBXIP1	TRAF7
Description		PBX homeobox interacting protein 1	TNF receptor associated factor 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Microtubule Membrane	Ubiquitin Ligase Complex Nucleolus Plasma Membrane Cytoplasmic Vesicle Intracellular Membrane-bounded Organelle
	Molecular Function	Transcription Corepressor Activity Protein Binding	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding
	Biological Process	Multicellular Organism Development Cell Differentiation Negative Regulation Of Transcription, DNA-templated Regulation Of Rho Guanyl-nucleotide Exchange Factor Activity	Ribosomal Large Subunit Assembly Activation Of MAPKKK Activity Apoptotic Process Notch Signaling Pathway Protein Ubiquitination Positive Regulation Of MAPK Cascade Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Apoptotic Signaling Pathway
Pathways			Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Inflammatory bowel disease ( 27569725) Prostate cancer ( 23535732)	Diastolic blood pressure ( 30578418) Height ( 28552196) Pulse pressure ( 30578418) Systolic blood pressure ( 30578418)
Interacting Genes		27 interacting genes: BRPF1 CAMLG CAPN2 CCDC85B CCNC DAXX DEF6 DPPA2 ESR1 GABARAPL1 GMCL1 GRB2 KRTAP10-6 LCA5L MDFI MDM2 MORF4L1 PCBD2 PPTC7 PRKAA2 SGTA TSNAX UBQLN1 UBQLN4 WASHC3 ZMYND8 ZZZ3	12 interacting genes: CDC42 CYLD MAP3K3 OGT RIPK4 TRAF6 UBE2D1 UBE2D2 UBE2D4 UBE2K UBE2L3 UBE2L6
Entrez ID		57326	84231
HPRD ID		17823	06977
Ensembl ID		ENSG00000163346	ENSG00000131653
Uniprot IDs		B4E0K4 Q96AQ6	B3KQY7 Q6Q0C0
PDB IDs
Enriched GO Terms of Interacting Partners?
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