ERGIC1 and NFIC

Data Source:
BioGRID (biochemical)

		ERGIC1	NFIC
Description		endoplasmic reticulum-golgi intermediate compartment 1	nuclear factor I C
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Endoplasmic Reticulum Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane COPII-coated ER To Golgi Transport Vesicle Integral Component Of Golgi Membrane Integral Component Of Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Intracellular Membrane-bounded Organelle	Chromatin Fibrillar Center Nucleus Nucleoplasm
	Molecular Function	Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Sequence-specific Double-stranded DNA Binding
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum	Negative Regulation Of Transcription By RNA Polymerase II DNA Replication Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II
Pathways			RNA Polymerase III Transcription Termination RNA Polymerase III Abortive And Retractive Initiation
Drugs
Diseases
GWAS		Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel) ( 23648065) Inflammatory bowel disease ( 28067908) Periodontitis (CDC/AAP) ( 24024966)	Alzheimer's disease (APOE e4 interaction) ( 28183528) Apolipoprotein A1 levels ( 32203549) Automobile speeding propensity ( 30643258) HDL cholesterol ( 30275531) HDL cholesterol levels ( 32203549) Heel bone mineral density ( 30598549) Height ( 28552196 20881960 25282103 31562340) High light scatter reticulocyte count ( 32888494) Hip circumference ( 28552196) Hip circumference adjusted for BMI ( 28552196) Nevus count or cutaneous melanoma ( 30429480) Platelet count ( 32888494) Plateletcrit ( 32888494) Serum urate levels in chronic kidney disease ( 30181573) Weight ( 28552196) Youthful appearance (self-reported) ( 32339537)
Interacting Genes		2 interacting genes: EHHADH ERGIC3	25 interacting genes: CBLC CREBBP DACH1 EPHA2 FBXO7 GLIS1 GLIS2 GLRX LATS2 LLPH MAP2K3 MAPK14 MYC NFIB NSD3 RELA RFX1 SOX3 TEAD2 TH TKTL2 TLX1 TPD52L3 ZCCHC14 ZKSCAN7
Entrez ID		57222	4782
HPRD ID		13836	09009
Ensembl ID		ENSG00000113719	ENSG00000141905
Uniprot IDs		Q969X5	B7Z4T6 P08651
PDB IDs
Enriched GO Terms of Interacting Partners?
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