AVEN and PMPCA

Data Source:
BioGRID (affinity chromatography technology)

		AVEN	PMPCA
Description		apoptosis and caspase activation inhibitor	peptidase, mitochondrial processing subunit alpha
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Endomembrane System Membrane	Extracellular Space Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix
	Molecular Function	Protein Binding	Protein Binding Metal Ion Binding
	Biological Process	Apoptotic Process Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Apoptotic Process	Protein Processing Involved In Protein Targeting To Mitochondrion Mitochondrial Calcium Ion Transmembrane Transport
Pathways		Formation of apoptosome Regulation of the apoptosome activity	Mitochondrial protein import Processing of SMDT1
Drugs
Diseases
GWAS		Malaria ( 31844061)	Apolipoprotein B levels ( 32203549) Chronotype ( 30696823) Crohn's disease ( 28067908) Granulocyte count ( 27863252) Inflammatory bowel disease ( 28067908 23128233) Joint damage in rheumatoid arthritis ( 26498133) LDL cholesterol levels ( 32203549) Myeloid white cell count ( 27863252) Neutrophil count ( 27863252) Serum total protein level ( 29403010) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) Ulcerative colitis ( 28067908) White blood cell count ( 27863252)
Interacting Genes		3 interacting genes: APAF1 BCL2L1 SMURF1	5 interacting genes: BMPR2 LINC01554 PMPCB SKIV2L ZNF76
Entrez ID		57099	23203
HPRD ID		05588	07500
Ensembl ID		ENSG00000169857	ENSG00000165688
Uniprot IDs		Q9NQS1	Q10713
PDB IDs
Enriched GO Terms of Interacting Partners?
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