RGMA and CRTC3

Data Source:
BioGRID (proximity labelling technology)

		RGMA	CRTC3
Description		repulsive guidance molecule BMP co-receptor a	CREB regulated transcription coactivator 3
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Plasma Membrane Anchored Component Of Membrane	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Protein Binding Coreceptor Activity Transferrin Receptor Binding	Protein Binding CAMP Response Element Binding Protein Binding
	Biological Process	BMP Signaling Pathway Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Axon Regeneration	Viral Process Positive Regulation Of CREB Transcription Factor Activity Macrophage Activation Negative Regulation Of CAMP-mediated Signaling Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Lipid Catabolic Process Protein Homotetramerization Energy Homeostasis
Pathways		Netrin-1 signaling	Transcriptional activation of mitochondrial biogenesis Circadian Clock
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Copper levels ( 26025379) HDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535) Heel bone mineral density ( 30598549) Metabolite levels ( 23823483) Opioid dependence ( 29478698) Overweight status ( 25133637) Periodontitis (CDC/AAP) ( 24024966) Refractive error ( 32231278) Response to angiotensin II receptor blocker therapy (opposite direction w/ diuretic therapy) ( 22566498) Type 1 diabetes nephropathy ( 23028342) Type 2 diabetes ( 32499647)	Apolipoprotein B levels ( 32203549) Chromium levels ( 26025379) Chronic postoperative pain ( 31903573) Colorectal cancer ( 29228715) Daytime sleep phenotypes ( 27126917) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Gastroesophageal reflux disease ( 27485664) Heel bone mineral density ( 28869591) Inflammatory bowel disease ( 28067908 23128233) Information processing speed ( 21130836) Male-pattern baldness ( 28196072) Offspring birth weight ( 31043758) Response to exercise (triglyceride level interaction) ( 26491034) Ulcerative colitis ( 28067908)
Interacting Genes		4 interacting genes: PPP1R16A SGSM2 TERF2IP TP53BP2	4 interacting genes: CA13 KLHL12 SIK2 YWHAG
Entrez ID		56963	64784
HPRD ID		09560	13384
Ensembl ID		ENSG00000182175	ENSG00000140577
Uniprot IDs		A0A0A0MTQ4 Q96B86	Q6UUV7 Q8TEF4
PDB IDs		4UHY 6Z3G
Enriched GO Terms of Interacting Partners?
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