PSKH1 and HPR

Data Source:
HPRD (in vitro)

		PSKH1	HPR
Description		protein serine kinase H1	haptoglobin-related protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Golgi Apparatus Microtubule Organizing Center Cytosol Plasma Membrane Nuclear Speck	Extracellular Region Extracellular Space Spherical High-density Lipoprotein Particle Extracellular Exosome Blood Microparticle
	Molecular Function	Protein Binding ATP Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity	Serine-type Endopeptidase Activity Hemoglobin Binding
	Biological Process	Protein Phosphorylation Determination Of Left/right Symmetry Heart Development	Acute Inflammatory Response Receptor-mediated Endocytosis Positive Regulation Of Cell Death Zymogen Activation
Pathways			Scavenging of heme from plasma
Drugs			Zinc Copper Zinc acetate
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) HDL cholesterol ( 30275531) HDL cholesterol levels ( 32203549) HDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535) HDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535) Hemoglobin ( 32888494) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular volume ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656)	Blood protein levels ( 28240269) Cholesterol, total ( 24097068 28270201 25961943 20686565 26582766) Coronary artery disease ( 32469254 33020668) Hematocrit ( 32888494) LDL cholesterol ( 24097068 25961943 20686565 26582766) LDL cholesterol levels ( 28334899 30698716) LDL cholesterol levels in current drinkers ( 30698716) LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) LDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535) LDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535) Liver enzyme levels (alkaline phosphatase) ( 22001757) Low density lipoprotein cholesterol levels ( 32154731) Metabolite levels ( 22916037) Serum metabolite levels ( 31636271) Serum metabolite levels (CMS) ( 31636271) Total cholesterol levels ( 28334899) Triglyceride levels ( 32154731) Triglyceride levels in current drinkers ( 30698716) Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
Interacting Genes		3 interacting genes: CDC6 RDH13 SNTA1	3 interacting genes: APOA1 IGHM VKORC1
Entrez ID		5681	3250
HPRD ID		01511	00773
Ensembl ID		ENSG00000159792	ENSG00000261701
Uniprot IDs		P11801	P00739
PDB IDs
Enriched GO Terms of Interacting Partners?
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