TMPRSS15 and RPS4Y1

Data Source:
BioGRID (affinity chromatography technology)

		TMPRSS15	RPS4Y1
Description		transmembrane serine protease 15	ribosomal protein S4 Y-linked 1
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GO Annotations	Cellular Component	Brush Border Membrane Integral Component Of Membrane	Nucleus Nucleoplasm Cytosol Polysome Membrane Cytosolic Small Ribosomal Subunit
	Molecular Function	Serine-type Endopeptidase Activity Scavenger Receptor Activity Protein Binding	RNA Binding Structural Constituent Of Ribosome Protein Binding RRNA Binding
	Biological Process	Proteolysis Endocytosis	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation SRP-dependent Cotranslational Protein Targeting To Membrane Multicellular Organism Development Viral Transcription
Pathways			L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases		Enterokinase deficiency
GWAS		Asthma ( 29273806) Bulimia nervosa ( 23568457) Nucleus accumbens volume in trauma-exposed individuals ( 29187748)
Interacting Genes		1 interacting genes: SPINK1	3 interacting genes: CALM1 CLK1 MEOX2
Entrez ID		5651	6192
HPRD ID		05972	15963
Ensembl ID		ENSG00000154646	ENSG00000129824
Uniprot IDs		P98073	P22090
PDB IDs		4DGJ 6ZOV	5AJ0 5FLX 6OLG 6OLZ
Enriched GO Terms of Interacting Partners?
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