SLC7A10 and TNFRSF9

Data Source:
HPRD (in vitro)

		SLC7A10	TNFRSF9
Description		solute carrier family 7 member 10	TNF receptor superfamily member 9
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Membrane	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane
	Molecular Function	Protein Binding Neutral Amino Acid Transmembrane Transporter Activity L-amino Acid Transmembrane Transporter Activity L-serine Transmembrane Transporter Activity	Protein Binding Cytokine Binding Signaling Receptor Activity
	Biological Process	Amino Acid Transmembrane Transport Amino Acid Transport Neutral Amino Acid Transport L-serine Transport D-alanine Transport D-serine Transport Leukocyte Migration L-alpha-amino Acid Transmembrane Transport	Apoptotic Process Negative Regulation Of Cell Population Proliferation Tumor Necrosis Factor-mediated Signaling Pathway Regulation Of Cell Population Proliferation
Pathways		Basigin interactions Amino acid transport across the plasma membrane	TNFs bind their physiological receptors
Drugs			Urelumab
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406 29785011) Allergic rhinitis ( 30013184) Asthma ( 31361310 31959851 30929738 32296059 31619474) Asthma (adult onset) ( 30929738) Asthma (childhood onset) ( 30929738) Asthma or allergic disease (pleiotropy) ( 29785011) Eosinophil counts ( 32888494) Medication use (adrenergics, inhalants) ( 31015401) Medication use (glucocorticoids) ( 31015401) Multiple sclerosis ( 31604244) Red blood cell count ( 29403010) Triglyceride levels ( 32203549) Visceral adipose tissue adjusted for BMI ( 22589738) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738) White blood cell count (basophil) ( 29403010)	Blond vs. brown/black hair color ( 30531825) Celiac disease ( 20190752) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908 23128233) Psoriasis ( 25903422 23143594) Rheumatoid arthritis ( 30423114 24390342) Ulcerative colitis ( 28067908 21297633) Waist-hip ratio ( 28552196)
Interacting Genes		2 interacting genes: APPBP2 SLC3A2	7 interacting genes: LRR1 SERP1 TNFRSF4 TNFSF9 TRAF1 TRAF2 TRAF3
Entrez ID		56301	3604
HPRD ID		12137	03767
Ensembl ID		ENSG00000130876	ENSG00000049249
Uniprot IDs		Q9NS82	Q07011
PDB IDs			6A3V 6A3W 6BWV 6CPR 6CU0 6MGP 6MHR 6MI2
Enriched GO Terms of Interacting Partners?
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