KLHL4 and RPL36

Data Source:
BioGRID (genetic interference)

		KLHL4	RPL36
Description		kelch like family member 4	ribosomal protein L36
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Microtubule Cytoskeleton Centriolar Satellite	Nucleolus Cytoplasm Cytosol Membrane Cytosolic Large Ribosomal Subunit Polysomal Ribosome
	Molecular Function	Molecular_function Actin Binding	RNA Binding Structural Constituent Of Ribosome
	Biological Process	Biological_process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Cytoplasmic Translation Translation Translational Initiation SRP-dependent Cotranslational Protein Targeting To Membrane Viral Transcription
Pathways			L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS		Alzheimer's disease ( 30636644)
Interacting Genes			4 interacting genes: APP DUX4 PTEN RPL18A
Entrez ID		56062	25873
HPRD ID		02283	10201
Ensembl ID		ENSG00000102271	ENSG00000130255
Uniprot IDs		A5PKX1 Q9C0H6	Q9Y3U8
PDB IDs			4UG0 4V6X 5AJ0 5LKS 5T2C 6EK0 6IP5 6IP6 6IP8 6LQM 6LSR 6LSS 6LU8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6W6L 6XA1 6Y0G 6Y2L 6Y57 6Y6X 6Z6L 6Z6M 6Z6N 6ZM7 6ZME 6ZMI 6ZMO
Enriched GO Terms of Interacting Partners?
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