CFC1 and TSN

Data Source:
BioGRID (proximity labelling technology)

		CFC1	TSN
Description		cripto, FRL-1, cryptic family 1	translin
Image		No pdb structure
GO Annotations	Cellular Component	Cellular_component Extracellular Region Plasma Membrane Cell Surface Anchored Component Of Membrane	Nucleus Nucleoplasm Cytoplasm Endoplasmic Reticulum Cytosol
	Molecular Function	Molecular_function Signaling Receptor Binding Nodal Binding Activin Receptor Binding	DNA Binding Single-stranded DNA Binding RNA Binding Endoribonuclease Activity Protein Binding Identical Protein Binding Sequence-specific DNA Binding Protein-containing Complex Binding
	Biological Process	Blood Vessel Development Determination Of Left/right Symmetry Gastrulation Heart Development Anterior/posterior Pattern Specification Nodal Signaling Pathway Anatomical Structure Development	DNA Recombination Production Of SiRNA Involved In RNA Interference RNA Phosphodiester Bond Hydrolysis, Endonucleolytic
Pathways		Signaling by NODAL Regulation of signaling by NODAL	Small interfering RNA (siRNA) biogenesis
Drugs
Diseases		Conotruncal heart malformations, including: Double-outlet right ventricle; Persistent truncus arteriosus; Conotruncal anomaly face syndrome Heterotaxy; Situs ambiguus
GWAS			Diastolic blood pressure ( 27841878) Disease progression in age-related macular degeneration ( 29346644) Erectile dysfunction and prostate cancer treatment ( 20932654) Food antigen IgG levels ( 24962563) Hepcidin/ferritin ratio ( 27846281) Paclitaxel disposition in epithelial ovarian cancer ( 29367611) Smoking status (ever vs never smokers) ( 30643258)
Interacting Genes			13 interacting genes: DVL3 GIT2 GORASP2 LNX1 MORF4L2 NTAQ1 PICK1 PPP1R15A SDCBP TSNAX UBE2I UBE2K ZBTB18
Entrez ID		55997	7247
HPRD ID		05548	08993
Ensembl ID		ENSG00000136698	ENSG00000211460
Uniprot IDs		A0A087WWV2 A0A087WX98 P0CG37	B3KRM8 Q15631
PDB IDs			1J1J 3PJA 3QB5 4WYV
Enriched GO Terms of Interacting Partners?
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