SULF2 and WFDC12

Data Source:
BioGRID (affinity chromatography technology)

		SULF2	WFDC12
Description		sulfatase 2	WAP four-disulfide core domain 12
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Endoplasmic Reticulum Golgi Stack Plasma Membrane Cell Surface	Extracellular Space
	Molecular Function	Arylsulfatase Activity Calcium Ion Binding Glycosaminoglycan Binding N-acetylglucosamine-6-sulfatase Activity	Serine-type Endopeptidase Inhibitor Activity Protein Binding
	Biological Process	Kidney Development Chondrocyte Development Glomerular Filtration Response To Wounding Positive Regulation Of Vascular Endothelial Growth Factor Production Esophagus Smooth Muscle Contraction Positive Regulation Of Wnt Signaling Pathway Heparan Sulfate Proteoglycan Metabolic Process Glomerular Basement Membrane Development Glial Cell-derived Neurotrophic Factor Receptor Signaling Pathway Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Embryonic Skeletal System Development Cartilage Development Bone Development Innervation Positive Regulation Of Canonical Wnt Signaling Pathway Liver Regeneration Regulation Of Hepatocyte Proliferation	Negative Regulation Of Endopeptidase Activity Antibacterial Humoral Response Defense Response To Bacterium Innate Immune Response
Pathways
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Attention deficit hyperactivity disorder (time to onset) ( 18937294) Cerebrospinal fluid AB1-42 levels ( 28247064) Depressive symptoms x herpes simplex 1 infection interaction ( 32564518) HDL cholesterol ( 30275531) HDL cholesterol levels ( 32203549) L-selectin levels ( 25576479) Nephrotic syndrome (acquired) ( 21441931) Nicotine dependence and major depression (severity of comorbidity) ( 30287806) Post bronchodilator FEV1/FVC ratio in COPD ( 26634245)	Bipolar disorder ( 31043756)
Interacting Genes			6 interacting genes: ASPH SGTA SGTB SLC39A7 UBQLN1 UBQLN2
Entrez ID		55959	128488
HPRD ID		18130	15674
Ensembl ID		ENSG00000196562	ENSG00000168703
Uniprot IDs		Q8IWU5	Q8WWY7
PDB IDs
Enriched GO Terms of Interacting Partners?
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