KIZ and OVOL2

Data Source:
HPRD (in vivo)

		KIZ	OVOL2
Description		kizuna centrosomal protein	ovo like zinc finger 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centrosome Cell Projection	Nucleus
	Molecular Function	Protein Binding Protein Kinase Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Chromatin Binding Protein Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Spindle Organization	Negative Regulation Of Transcription By RNA Polymerase II Angiogenesis Neural Crest Cell Migration Neural Fold Formation Heart Looping Regulation Of Transcription By RNA Polymerase II Epidermal Cell Differentiation Dorsal/ventral Pattern Formation Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Negative Regulation Of Epithelial To Mesenchymal Transition Regulation Of Keratinocyte Proliferation Positive Regulation Of Keratinocyte Differentiation Positive Regulation Of Transcription By RNA Polymerase II Embryonic Digestive Tract Morphogenesis Endocardium Formation Heart Trabecula Formation Regulation Of SMAD Protein Signal Transduction Labyrinthine Layer Blood Vessel Development Cellular Response To Transforming Growth Factor Beta Stimulus Negative Regulation Of Stem Cell Proliferation
Pathways
Drugs
Diseases
GWAS		anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder ( 30804558) Height ( 31562340)	Low density lipoprotein cholesterol levels ( 32154731) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Nicotine dependence symptom count ( 25555482) Red blood cell count ( 32888494)
Interacting Genes		3 interacting genes: MEOX2 TACC3 TFIP11	2 interacting genes: PARP1 ZNF526
Entrez ID		55857	58495
HPRD ID		12760	15780
Ensembl ID		ENSG00000088970	ENSG00000125850
Uniprot IDs		A0A087X251 Q2M2Z5	Q9BRP0
PDB IDs
Enriched GO Terms of Interacting Partners?
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