TMEM127 and LMAN2L

Data Source:
BioGRID (affinity chromatography technology)

		TMEM127	LMAN2L
Description		transmembrane protein 127	lectin, mannose binding 2 like
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Early Endosome Plasma Membrane Membrane Integral Component Of Membrane	Golgi Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Integral Component Of Membrane COPII-coated ER To Golgi Transport Vesicle
	Molecular Function	Molecular_function Small GTPase Binding	Protein Binding Mannose Binding Metal Ion Binding
	Biological Process	Endosome Organization Negative Regulation Of Cell Population Proliferation Regulation Of TOR Signaling Negative Regulation Of TOR Signaling	Protein Folding Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Endoplasmic Reticulum Organization Golgi Organization Protein Transport
Pathways			COPII-mediated vesicle transport Cargo concentration in the ER
Drugs
Diseases
GWAS		Type 2 diabetes (adjusted for BMI) ( 30297969)	anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Bipolar disorder ( 22182935 21926972 31043756 28072414 20351715) Blood protein levels ( 30072576 29875488)
Interacting Genes			2 interacting genes: MAL ZDHHC17
Entrez ID		55654	81562
HPRD ID		07917	17286
Ensembl ID		ENSG00000135956	ENSG00000114988
Uniprot IDs		C9J4H2 O75204 Q9H6I0	B4DI83 B4DVH1 B4E308 Q9H0V9
PDB IDs
Enriched GO Terms of Interacting Partners?
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