SMPD4 and CFC1

Data Source:
BioGRID (affinity chromatography technology)

		SMPD4	CFC1
Description		sphingomyelin phosphodiesterase 4	cripto, FRL-1, cryptic family 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Nuclear Envelope Nuclear Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Trans-Golgi Network Integral Component Of Membrane Sarcolemma	Cellular_component Extracellular Region Plasma Membrane Cell Surface Anchored Component Of Membrane
	Molecular Function	Sphingomyelin Phosphodiesterase Activity Metal Ion Binding Sphingomyelin Phosphodiesterase D Activity	Molecular_function Signaling Receptor Binding Nodal Binding Activin Receptor Binding
	Biological Process	Sphingomyelin Catabolic Process Glycosphingolipid Metabolic Process Endoplasmic Reticulum Organization Glycerophospholipid Catabolic Process Ceramide Biosynthetic Process Cellular Response To Tumor Necrosis Factor	Blood Vessel Development Determination Of Left/right Symmetry Gastrulation Heart Development Anterior/posterior Pattern Specification Nodal Signaling Pathway Anatomical Structure Development
Pathways		Glycosphingolipid metabolism	Signaling by NODAL Regulation of signaling by NODAL
Drugs		Phosphatidyl serine
Diseases			Conotruncal heart malformations, including: Double-outlet right ventricle; Persistent truncus arteriosus; Conotruncal anomaly face syndrome Heterotaxy; Situs ambiguus
GWAS
Interacting Genes		2 interacting genes: ERBB2 EXOSC4
Entrez ID		55627	55997
HPRD ID		13374	05548
Ensembl ID		ENSG00000136699	ENSG00000136698
Uniprot IDs		Q9NXE4	A0A087WWV2 A0A087WX98 P0CG37
PDB IDs
Enriched GO Terms of Interacting Partners?
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