PRIM2 and GTF3C6

Data Source:
BioGRID (affinity chromatography technology)

		PRIM2	GTF3C6
Description		DNA primase subunit 2	general transcription factor IIIC subunit 6
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Alpha DNA Polymerase:primase Complex	Transcription Factor TFIIIC Complex Nucleoplasm Nuclear Body
	Molecular Function	DNA Binding Protein Binding Metal Ion Binding 4 Iron, 4 Sulfur Cluster Binding	DNA Binding Protein Binding
	Biological Process	G1/S Transition Of Mitotic Cell Cycle DNA Replication, Synthesis Of RNA Primer DNA Replication Initiation Telomere Maintenance Via Semi-conservative Replication	Transcription By RNA Polymerase III 5S Class RRNA Transcription By RNA Polymerase III TRNA Transcription By RNA Polymerase III
Pathways		Inhibition of replication initiation of damaged DNA by RB1/E2F1 Polymerase switching on the C-strand of the telomere Telomere C-strand synthesis initiation DNA replication initiation Activation of the pre-replicative complex Polymerase switching Removal of the Flap Intermediate Processive synthesis on the lagging strand	RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter
Drugs
Diseases
GWAS		Chronotype ( 30696823) Coronary artery disease ( 33020668) Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid) ( 24823311) Systemic lupus erythematosus ( 28714469)	Refractive error ( 32231278)
Interacting Genes		6 interacting genes: KDM1A POLA1 POLA2 PRIM1 RECK SUV39H1	4 interacting genes: APP GTF3C4 GTF3C5 SPATC1L
Entrez ID		5558	112495
HPRD ID		08900	12886
Ensembl ID		ENSG00000146143	ENSG00000155115
Uniprot IDs		A0A024RD43 P49643	Q969F1
PDB IDs		3L9Q 3Q36 4BPU 4BPW 4BPX 4RR2 5DQO 5EXR 5F0Q 5F0S 5I7M 6DHW
Enriched GO Terms of Interacting Partners?
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