PLXNA3 and SFTPD

Data Source:
BioGRID (pull down)

		PLXNA3	SFTPD
Description		plexin A3	surfactant protein D
Image		No pdb structure
GO Annotations	Cellular Component	Semaphorin Receptor Complex Plasma Membrane Integral Component Of Plasma Membrane Membrane	Extracellular Region Collagen Trimer Extracellular Space Lysosome Multivesicular Body Endoplasmic Reticulum Membrane Rough Endoplasmic Reticulum Endocytic Vesicle Clathrin-coated Endocytic Vesicle
	Molecular Function	Transmembrane Signaling Receptor Activity Protein Binding Semaphorin Receptor Activity	Protein Binding Carbohydrate Binding
	Biological Process	Negative Regulation Of Cell Adhesion Multicellular Organism Development Regulation Of Cell Shape Facial Nerve Structural Organization Trigeminal Nerve Structural Organization Hippocampus Development Branchiomotor Neuron Axon Guidance Pyramidal Neuron Development Regulation Of Cell Migration Regulation Of GTPase Activity Negative Regulation Of Axon Extension Involved In Axon Guidance Positive Regulation Of Axonogenesis Negative Chemotaxis Positive Regulation Of Cytoskeleton Organization Semaphorin-plexin Signaling Pathway Semaphorin-plexin Signaling Pathway Involved In Axon Guidance Neuron Projection Extension	Regulation Of Cytokine Production Toll-like Receptor Signaling Pathway Receptor-mediated Endocytosis Respiratory Gaseous Exchange By Respiratory System Negative Regulation Of Interleukin-2 Production Negative Regulation Of T Cell Proliferation Defense Response To Bacterium Surfactant Homeostasis Induction Of Bacterial Agglutination Cellular Protein Metabolic Process Innate Immune Response Macrophage Chemotaxis Lung Alveolus Development Positive Regulation Of Phagocytosis Regulation Of Immune Response Negative Regulation By Host Of Symbiont Molecular Function Reactive Oxygen Species Metabolic Process Regulation Of Adhesion Of Symbiont To Host Epithelial Cell
Pathways		Sema3A PAK dependent Axon repulsion SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion CRMPs in Sema3A signaling CRMPs in Sema3A signaling	Toll Like Receptor 4 (TLR4) Cascade Toll Like Receptor TLR1:TLR2 Cascade Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Signal regulatory protein family interactions Surfactant metabolism Regulation of TLR by endogenous ligand Defective CSF2RB causes SMDP5 Defective CSF2RA causes SMDP4
Drugs			Beta-D-Glucose
Diseases
GWAS			Chronic obstructive pulmonary disease ( 28166215 30804561) Chronic obstructive pulmonary disease-related biomarkers ( 23144326) Lung function (FEV1/FVC) ( 30804560) Rheumatoid arthritis ( 30423114 24390342)
Interacting Genes		8 interacting genes: CSNK2B MAPK8IP2 MTDH PPP2CB SMN1 TK1 TRIM55 TRIM63	3 interacting genes: DCN DMBT1 MFAP4
Entrez ID		55558	6441
HPRD ID		02062	01522
Ensembl ID		ENSG00000130827	ENSG00000133661
Uniprot IDs		P51805	P35247
PDB IDs			1B08 1M7L 1PW9 1PWB 2GGU 2GGX 2ORJ 2ORK 2OS9 2RIA 2RIB 2RIC 2RID 2RIE 3DBZ 3G81 3G83 3G84 3IKN 3IKP 3IKQ 3IKR 4E52 4M17 4M18 5OXR 5OXS
Enriched GO Terms of Interacting Partners?
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