DNAJA4 and HYKK

Data Source:
HPRD (in vivo)

		DNAJA4	HYKK
Description		DnaJ heat shock protein family (Hsp40) member A4	hydroxylysine kinase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Membrane	Mitochondrial Matrix
	Molecular Function	Protein Binding ATP Binding Heat Shock Protein Binding Metal Ion Binding Unfolded Protein Binding Chaperone Binding	Amino Acid Kinase Activity Hydroxylysine Kinase Activity
	Biological Process	Response To Heat Negative Regulation Of Endothelial Cell Migration Positive Regulation Of Gene Expression Protein Refolding Negative Regulation Of Inclusion Body Assembly	Lysine Catabolic Process Phosphorylation
Pathways		HSP90 chaperone cycle for steroid hormone receptors (SHR)	Lysine catabolism
Drugs
Diseases
GWAS		Eyebrow thickness ( 26926045) Hematocrit ( 32888494) Hemoglobin levels ( 32327693) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Intracranial aneurysm ( 29531279) Mean corpuscular volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Platelet count ( 32888494) Plateletcrit ( 32888494) Red cell distribution width ( 32888494 27863252 28957414) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252)	Autism spectrum disorder or schizophrenia ( 28540026) Schizophrenia ( 29483656)
Interacting Genes		3 interacting genes: BANP ERG SH3BP4	3 interacting genes: GMCL1 LAGE3 TRIP6
Entrez ID		55466	123688
HPRD ID		09920	12515
Ensembl ID		ENSG00000140403	ENSG00000188266
Uniprot IDs		Q69YX3 Q8WW22	A2RU49
PDB IDs
Enriched GO Terms of Interacting Partners?
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