TMEM33 and SIX6

Data Source:
BioGRID (affinity chromatography technology)

		TMEM33	SIX6
Description		transmembrane protein 33	SIX homeobox 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Envelope Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Endoplasmic Reticulum Membrane Melanosome	Chromatin Nucleus Transcription Regulator Complex
	Molecular Function	Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Sequence-specific Double-stranded DNA Binding
	Biological Process	Response To Endoplasmic Reticulum Stress Membrane Organization Endoplasmic Reticulum Tubular Network Organization Regulation Of Endoplasmic Reticulum Tubular Network Organization Positive Regulation Of IRE1-mediated Unfolded Protein Response Positive Regulation Of PERK-mediated Unfolded Protein Response	Eye Development Regulation Of Transcription By RNA Polymerase II Visual Perception Animal Organ Morphogenesis
Pathways
Drugs
Diseases			Anophthalmia and microphthalmia (A/M)
GWAS		Helping behaviour (self reported) ( 29324852) Neurociticism ( 29500382)	Exhaled carbon monoxide levels in smokers with chronic obstructive pulmonary disease ( 29631575) Glaucoma ( 30054594) Glaucoma (primary open-angle) ( 22419738 29891935 25173105 29452408 22570617) Gut microbiota (bacterial taxa) ( 27723756) Height ( 20881960 25429064) Medication use (antiglaucoma preparations and miotics) ( 31015401) Menarche (age at onset) ( 25231870) Optic cup area ( 25631615 31798171 28073927) Optic disc area ( 25631615 31798171 28073927) Refractive error ( 23396134 32231278) Spherical equivalent (joint analysis main effects and education interaction) ( 27020472) Urinary sodium excretion ( 31409800) Vertical cup-disc ratio ( 31798171 25241763 28073927)
Interacting Genes		3 interacting genes: MTNR1A RPS14 SLC29A2	3 interacting genes: GTF2A1L TLE1 TLE5
Entrez ID		55161	4990
HPRD ID		07680	07557
Ensembl ID		ENSG00000109133	ENSG00000184302
Uniprot IDs		A0A024R9W7 P57088	O95475 Q6P051
PDB IDs
Enriched GO Terms of Interacting Partners?
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