MKS1 and DGKE

Data Source:
BioGRID (affinity chromatography technology)

		MKS1	DGKE
Description		MKS transition zone complex subunit 1	diacylglycerol kinase epsilon
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centrosome Cytosol MKS Complex Ciliary Basal Body	Nucleoplasm Cytoplasm Cytosol Plasma Membrane Membrane Integral Component Of Membrane Glutamatergic Synapse
	Molecular Function	Protein Binding	NAD+ Kinase Activity Diacylglycerol Kinase Activity ATP Binding Kinase Activity Metal Ion Binding
	Biological Process	Cilium Assembly Ciliary Basal Body-plasma Membrane Docking	Phosphatidic Acid Biosynthetic Process Phosphatidylinositol Biosynthetic Process Protein Kinase C-activating G Protein-coupled Receptor Signaling Pathway Platelet Activation Intracellular Signal Transduction Diacylglycerol Metabolic Process Lipid Phosphorylation Modulation Of Chemical Synaptic Transmission
Pathways		Hedgehog 'off' state Anchoring of the basal body to the plasma membrane	Effects of PIP2 hydrolysis
Drugs			alpha-Tocopherol succinate
Diseases		Bardet-Biedl syndrome (BBS) Meckel syndrome (MKS); Meckel-Gruber syndrome
GWAS		Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Post bronchodilator FEV1 in COPD ( 26634245) Post bronchodilator FEV1/FVC ratio in COPD ( 26634245)	Crohn's disease ( 28067908) Early spontaneous preterm birth ( 31194736) Height ( 18391951) Refractive error ( 32231278) Retinal detachment or retinal break ( 31816047)
Interacting Genes		2 interacting genes: DDX24 TMEM67	2 interacting genes: HRAS MRPL44
Entrez ID		54903	8526
HPRD ID		07900	03259
Ensembl ID		ENSG00000011143	ENSG00000153933
Uniprot IDs		A0A0S2Z5Z2 B4DVC5 H0Y2S2 J3KSC6 Q9NXB0	A1L4Q0 P52429
PDB IDs
Enriched GO Terms of Interacting Partners?
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