CWC25 and GSDMB

Data Source:
BioGRID (affinity chromatography technology)

		CWC25	GSDMB
Description		CWC25 spliceosome associated protein homolog	gasdermin B
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GO Annotations	Cellular Component	Nucleus Nucleoplasm U2-type Spliceosomal Complex Nuclear Speck U2-type Catalytic Step 1 Spliceosome	Cellular_component Cytoplasm Plasma Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding	Phosphatidylserine Binding Molecular_function Phosphatidylinositol-4,5-bisphosphate Binding Phosphatidylinositol-4-phosphate Binding
	Biological Process	MRNA Splicing, Via Spliceosome	Cytolysis Defense Response To Bacterium Pyroptosis
Pathways		mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Intraocular pressure ( 29617998)	Adult asthma ( 30787307) Allergic disease (asthma, hay fever and/or eczema) (age of onset) ( 32603359) Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) ( 32603359) Allergic disease (asthma, hay fever or eczema) ( 29083406) Allergic rhinitis ( 30013184) Allergy ( 27182965) Asthma ( 21804549 31361310 31959851 30929738 20860503 32296059 31619474 29273806 28461288) Asthma (age of onset) ( 31036433) Asthma (childhood onset) ( 31036433 30929738 27611488 24241537 29273806) Asthma (time to onset) ( 27130862) Asthma onset (childhood vs adult) ( 30929738) Asthma or allergic disease (pleiotropy) ( 29785011) Atrial fibrillation ( 30061737) Bronchial hyperresponsiveness in asthma ( 27439200) Cervical cancer ( 23817570) Crohn's disease ( 28067908) Dermatomyositis or juvenile dermatomyositis ( 26362759) Feeling miserable ( 29500382) Fractional exhaled nitric oxide (childhood) ( 24315451) IgM levels ( 28628107) Inflammatory bowel disease ( 28067908 23128233) Medication use (adrenergics, inhalants) ( 31015401) Medication use (glucocorticoids) ( 31015401) Monocyte percentage of white cells ( 27863252) Primary biliary cholangitis ( 23000144 20639880 30643196) Primary biliary cirrhosis ( 22961000) Refractive error ( 32231278) Rheumatoid arthritis ( 23143596) Rheumatoid arthritis (ACPA-positive) ( 23143596 24532676) Self-reported allergy ( 23817569) Subcutaneous adipose tissue ( 27918534) Systemic lupus erythematosus ( 26502338) Systemic sclerosis ( 28314753 31672989) Type 1 diabetes ( 30659077 25751624) Ulcerative colitis ( 28067908) White blood cell count ( 32888494 21738480)
Interacting Genes		6 interacting genes: CCDC85B FMR1 KRT34 LAMC3 MDM2 TRIM21	8 interacting genes: AGT APP CLK1 HIVEP1 IGFBP2 ORM1 PEBP1 SERPINA1
Entrez ID		54883	55876
HPRD ID		07892	17082
Ensembl ID		ENSG00000273559	ENSG00000073605
Uniprot IDs		Q9NXE8	Q8TAX9
PDB IDs		5YZG 6ZYM	5TIB 5TJ2 5TJ4
Enriched GO Terms of Interacting Partners?
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