TMEM214 and IFT172

Data Source:
BioGRID (affinity chromatography technology)

		TMEM214	IFT172
Description		transmembrane protein 214	intraflagellar transport 172
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Cytoplasmic Microtubule Integral Component Of Membrane	Cilium Axoneme Intraciliary Transport Particle B Ciliary Basal Body Sperm Midpiece Sperm Principal Piece Ciliary Tip Sperm Cytoplasmic Droplet Extracellular Vesicle
	Molecular Function
	Biological Process	Apoptotic Process	Neural Tube Closure Heart Looping Notch Signaling Pathway Smoothened Signaling Pathway Brain Development Epidermis Development Dorsal/ventral Pattern Formation Protein Processing Spinal Cord Motor Neuron Differentiation Cytoplasmic Microtubule Organization Intraciliary Transport Involved In Cilium Assembly Intraciliary Transport Negative Regulation Of Smoothened Signaling Pathway Positive Regulation Of Smoothened Signaling Pathway Embryonic Camera-type Eye Morphogenesis Negative Regulation Of Epithelial Cell Proliferation Roof Of Mouth Development Limb Development Cilium Assembly Bone Development Hindgut Development Left/right Axis Specification Non-motile Cilium Assembly
Pathways			Hedgehog 'off' state Intraflagellar transport Intraflagellar transport
Drugs
Diseases
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Calcium levels ( 20705733) Chronic kidney disease ( 20383146) Crohn's disease ( 28067908) Hypertriglyceridemia ( 23505323) Inflammatory bowel disease ( 28067908) Total cholesterol levels ( 30718733)
Interacting Genes		2 interacting genes: LSM1 PJA1	2 interacting genes: LHX3 LHX4
Entrez ID		54867	26160
HPRD ID		07887	09576
Ensembl ID		ENSG00000119777	ENSG00000138002
Uniprot IDs		Q6NUQ4	A0A6Q8PGJ2 Q9UG01
PDB IDs
Enriched GO Terms of Interacting Partners?
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