GON4L and ATP6V1A

Data Source:
BioGRID (affinity chromatography technology)

		GON4L	ATP6V1A
Description		gon-4 like	ATPase H+ transporting V1 subunit A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Body	Nucleoplasm Lysosomal Membrane Cytosol Plasma Membrane Microvillus Apical Plasma Membrane Proton-transporting Two-sector ATPase Complex Proton-transporting V-type ATPase, V1 Domain Intracellular Membrane-bounded Organelle Extracellular Exosome
	Molecular Function	Transcription Coregulator Activity Transcription Corepressor Activity	ATP Binding ATPase Activity Proton-transporting ATP Synthase Activity, Rotational Mechanism Proton-transporting ATPase Activity, Rotational Mechanism
	Biological Process	Regulation Of Transcription, DNA-templated B Cell Differentiation Negative Regulation Of Transcription, DNA-templated	Cellular Iron Ion Homeostasis Insulin Receptor Signaling Pathway ATP Synthesis Coupled Proton Transport Regulation Of Macroautophagy Transferrin Transport Ion Transmembrane Transport Cellular Response To Increased Oxygen Levels Phagosome Acidification Proton Transmembrane Transport
Pathways			ROS and RNS production in phagocytes Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport
Drugs			Alendronic acid Etidronic acid Tiludronic acid Bafilomycin A1 Bafilomycin B1
Diseases
GWAS		Blood urea nitrogen levels ( 31152163) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body mass index ( 28892062) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Lewy body disease ( 25188341) Neuritic plaque ( 31497858) Periventricular white matter hyperintensities ( 32517579) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Urate levels ( 31578528)	Prostate cancer ( 23535732)
Interacting Genes		1 interacting genes: ITGB5	6 interacting genes: ANXA7 CDC42 CDKN1A SMN1 TK1 TUFM
Entrez ID		54856	523
HPRD ID		13370	06120
Ensembl ID		ENSG00000116580	ENSG00000114573
Uniprot IDs		A4PB67 A4PB68 Q14BN2 Q3T8J9 Q9H986	P38606
PDB IDs
Enriched GO Terms of Interacting Partners?
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