PPID and LARP1

Data Source:
BioGRID (affinity chromatography technology)

		PPID	LARP1
Description		peptidylprolyl isomerase D	La ribonucleoprotein 1, translational regulator
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol	Cytoplasm Polysome Cytoplasmic Stress Granule Membrane TORC1 Complex Polysomal Ribosome
	Molecular Function	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Transcription Factor Binding Cyclosporin A Binding Estrogen Receptor Binding Hsp70 Protein Binding Heat Shock Protein Binding Hsp90 Protein Binding	RNA Cap Binding RNA 7-methylguanosine Cap Binding RNA Binding MRNA 3'-UTR Binding Protein Binding Eukaryotic Initiation Factor 4E Binding Translation Activator Activity Translation Initiation Factor Binding Ribosomal Small Subunit Binding Cadherin Binding MRNA 5'-UTR Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Protein Peptidyl-prolyl Isomerization Protein Folding Apoptotic Process Protein Transport Viral Release From Host Cell Lipid Droplet Organization Positive Regulation Of Apoptotic Process Positive Regulation Of Viral Genome Replication Positive Regulation Of Protein Secretion Chaperone-mediated Protein Folding Protein-containing Complex Assembly Cellular Response To UV-A	Translational Initiation Cell Population Proliferation Posttranscriptional Regulation Of Gene Expression Positive Regulation Of Macroautophagy Negative Regulation Of Translation TOR Signaling TORC1 Signaling Positive Regulation Of Viral Genome Replication Negative Regulation Of Translational Initiation Positive Regulation Of Translational Initiation MRNA Stabilization Cellular Response To Rapamycin Response To Amino Acid Starvation
Pathways		ESR-mediated signaling
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 28240269) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Serum metabolite levels ( 23093944)	Chin dimples ( 27182965) High light scatter reticulocyte percentage of red cells ( 32888494) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Monobrow ( 27182965) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		20 interacting genes: APP BCL2 CSNK2B ESR1 FBXO25 FES HAP1 HSF1 HSP90AA1 HSP90AB1 HSPA8 KAT7 LNX1 PLK1 S100A1 S100A2 S100A6 SLC25A4 SMURF2 TRIM27	9 interacting genes: BCL2L1 CSNK2A1 KASH5 SRPK1 TNNT1 YWHAB YWHAG YWHAQ YWHAZ
Entrez ID		5481	23367
HPRD ID		11875	11225
Ensembl ID		ENSG00000171497	ENSG00000155506
Uniprot IDs		E5KN55 Q08752	Q6PKG0
PDB IDs			4ZC4 5C0V 5V4R 5V7C 5V87 6PW3
Enriched GO Terms of Interacting Partners?
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