CNNM2 and WBP1L

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo)

		CNNM2	WBP1L
Description		cyclin and CBS domain divalent metal cation transport mediator 2	WW domain binding protein 1 like
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Basolateral Plasma Membrane Intracellular Membrane-bounded Organelle	Integral Component Of Membrane
	Molecular Function	ATP Binding Magnesium Ion Transmembrane Transporter Activity Transmembrane Transporter Activity	Protein Binding
	Biological Process	Transport Magnesium Ion Homeostasis Magnesium Ion Transmembrane Transport
Pathways
Drugs
Diseases
GWAS		anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Anxiety/tension (special factor of neuroticism) ( 30867560) Arsenic metabolism ( 22383894) Autism spectrum disorder or schizophrenia ( 28540026) Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885) Blood pressure ( 21572416) Brain morphology (MOSTest) ( 32665545) Coronary artery disease ( 29212778 24262325 26343387 33020668) Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975) Coronary artery disease or large artery stroke ( 24262325) Coronary heart disease ( 21378990) Creatine kinase levels ( 29403010) Diastolic blood pressure ( 30487518) Estimated glomerular filtration rate ( 31015462) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Hypertension ( 31879980 30487518) Intracranial aneurysm ( 20364137) Mean arterial pressure ( 27618448 30487518) Mean corpuscular hemoglobin ( 32888494 27863252) Mean corpuscular hemoglobin concentration ( 32888494) Mean corpuscular volume ( 32888494 27863252) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Microalbuminuria ( 26631737) Myocardial infarction ( 26343387) Number of sexual partners ( 30643258) Parkinson's disease ( 19915575) Prostate cancer ( 23535732) Pulse pressure ( 30487518) Response to cognitive-behavioural therapy in major depressive disorder ( 31123309) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494) Schizophrenia ( 28991256 25056061 21926974 29483656 22688191 30285260 23974872 23894747) Smoking initiation ( 30617275) Systolic blood pressure ( 19430483 30487518 30578418) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) White blood cell count ( 32888494) White matter lesion progression ( 26451028)	Asthma ( 32296059) Autism spectrum disorder or schizophrenia ( 28540026) Body mass index ( 29273807) Brain morphology (MOSTest) ( 32665545) Carotid plaque burden ( 28282560) Chloride levels ( 29403010) Coronary artery disease ( 32469254) Diastolic blood pressure (long-term average) ( 28348047) Estimated glomerular filtration rate ( 31152163 31015462) Hematocrit ( 32888494) Hemoglobin levels ( 32327693) Hypertension ( 30487518) Mean arterial pressure ( 30487518) Mean arterial pressure (long-term average) ( 28348047) Monocyte count ( 27863252) Monocyte percentage of white cells ( 32888494) Prostate cancer ( 23535732) Pulse pressure ( 30487518) Red blood cell count ( 32888494) Schizophrenia ( 28991256 25056061 29483656 23974872) Sodium levels ( 29403010) Systolic blood pressure ( 30487518) Systolic blood pressure (long-term average) ( 28348047) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes			4 interacting genes: ABHD16A EPN2 LIG4 SGTA
Entrez ID		54805	54838
HPRD ID		07418	12567
Ensembl ID		ENSG00000148842	ENSG00000166272
Uniprot IDs		Q9H8M5	Q9NX94
PDB IDs		4IY0 4IY2 4IY4 4IYS 6DJ3 6N7E
Enriched GO Terms of Interacting Partners?
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