CNNM2 and DPCD

Data Source:
BioGRID (genetic interference)

		CNNM2	DPCD
Description		cyclin and CBS domain divalent metal cation transport mediator 2	deleted in primary ciliary dyskinesia homolog (mouse)
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Basolateral Plasma Membrane Intracellular Membrane-bounded Organelle	Extracellular Region Nucleus
	Molecular Function	ATP Binding Magnesium Ion Transmembrane Transporter Activity Transmembrane Transporter Activity	Protein Binding
	Biological Process	Transport Magnesium Ion Homeostasis Magnesium Ion Transmembrane Transport	Epithelial Cilium Movement Involved In Extracellular Fluid Movement Spermatogenesis Determination Of Left/right Symmetry Lateral Ventricle Development Third Ventricle Development Flagellated Sperm Motility Left/right Pattern Formation
Pathways
Drugs
Diseases
GWAS		anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Anxiety/tension (special factor of neuroticism) ( 30867560) Arsenic metabolism ( 22383894) Autism spectrum disorder or schizophrenia ( 28540026) Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885) Blood pressure ( 21572416) Brain morphology (MOSTest) ( 32665545) Coronary artery disease ( 29212778 24262325 26343387 33020668) Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975) Coronary artery disease or large artery stroke ( 24262325) Coronary heart disease ( 21378990) Creatine kinase levels ( 29403010) Diastolic blood pressure ( 30487518) Estimated glomerular filtration rate ( 31015462) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Hypertension ( 31879980 30487518) Intracranial aneurysm ( 20364137) Mean arterial pressure ( 27618448 30487518) Mean corpuscular hemoglobin ( 32888494 27863252) Mean corpuscular hemoglobin concentration ( 32888494) Mean corpuscular volume ( 32888494 27863252) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Microalbuminuria ( 26631737) Myocardial infarction ( 26343387) Number of sexual partners ( 30643258) Parkinson's disease ( 19915575) Prostate cancer ( 23535732) Pulse pressure ( 30487518) Response to cognitive-behavioural therapy in major depressive disorder ( 31123309) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494) Schizophrenia ( 28991256 25056061 21926974 29483656 22688191 30285260 23974872 23894747) Smoking initiation ( 30617275) Systolic blood pressure ( 19430483 30487518 30578418) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) White blood cell count ( 32888494) White matter lesion progression ( 26451028)	Mean corpuscular volume ( 32888494)
Interacting Genes			2 interacting genes: APP RUVBL2
Entrez ID		54805	25911
HPRD ID		07418	13247
Ensembl ID		ENSG00000148842	ENSG00000166171
Uniprot IDs		Q9H8M5	Q5JQQ4 Q9BVM2
PDB IDs		4IY0 4IY2 4IY4 4IYS 6DJ3 6N7E
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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