PPIC and TRAF7

Data Source:
BioGRID (biochemical)

		PPIC	TRAF7
Description		peptidylprolyl isomerase C	TNF receptor associated factor 7
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Intracellular Membrane-bounded Organelle Extracellular Exosome	Ubiquitin Ligase Complex Nucleolus Plasma Membrane Cytoplasmic Vesicle Intracellular Membrane-bounded Organelle
	Molecular Function	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Cyclosporin A Binding	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding
	Biological Process	Protein Peptidyl-prolyl Isomerization Protein Folding	Ribosomal Large Subunit Assembly Activation Of MAPKKK Activity Apoptotic Process Notch Signaling Pathway Protein Ubiquitination Positive Regulation Of MAPK Cascade Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Apoptotic Signaling Pathway
Pathways			Antigen processing: Ubiquitination & Proteasome degradation
Drugs		Proline
Diseases
GWAS		Aortic root size ( 19584346) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Diverticular disease ( 30177863) Subcortical volume (MOSTest) ( 32665545)	Diastolic blood pressure ( 30578418) Height ( 28552196) Pulse pressure ( 30578418) Systolic blood pressure ( 30578418)
Interacting Genes		13 interacting genes: ARSA BANP CAPNS2 FAM25A FAM25C FAM25G LGALS3BP SGTA SGTB UBAP1 UBQLN1 UBQLN2 UBQLN4	12 interacting genes: CDC42 CYLD MAP3K3 OGT RIPK4 TRAF6 UBE2D1 UBE2D2 UBE2D4 UBE2K UBE2L3 UBE2L6
Entrez ID		5480	84231
HPRD ID		00459	06977
Ensembl ID		ENSG00000168938	ENSG00000131653
Uniprot IDs		P45877	B3KQY7 Q6Q0C0
PDB IDs		2ESL
Enriched GO Terms of Interacting Partners?
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