NDFIP2 and ALKBH2

Data Source:
BioGRID (affinity chromatography technology, pull down)

		NDFIP2	ALKBH2
Description		Nedd4 family interacting protein 2	alkB homolog 2, alpha-ketoglutarate dependent dioxygenase
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Mitochondrion Endoplasmic Reticulum Golgi Apparatus Integral Component Of Membrane Multivesicular Body Membrane Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm	Nucleoplasm
	Molecular Function	Protein Binding WW Domain Binding	Protein Binding Ferrous Iron Binding DNA-N1-methyladenine Dioxygenase Activity Cytosine C-5 DNA Demethylase Activity 1-ethyladenine Demethylase Activity
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Vacuolar Transport Negative Regulation Of Gene Expression Metal Ion Transport Positive Regulation Of Protein Ubiquitination Negative Regulation Of Transporter Activity Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Protein Transport	DNA Dealkylation Involved In DNA Repair Oxidative DNA Demethylation Oxidative Demethylation DNA Demethylation
Pathways			ALKBH2 mediated reversal of alkylation damage
Drugs			Ascorbic acid
Diseases
GWAS		Leisure-time exercise behaviour (age-stratified) ( 30102679) Major depressive disorder ( 23377640) Metabolite levels ( 23823483) Pancreatic cancer ( 20686608) Smoking status (ever vs never smokers) ( 30643258) Youthful appearance (self-reported) ( 32339537)
Interacting Genes		8 interacting genes: AQP2 ITCH LYN NEDD4 NEDD4L SMURF1 UQCRH WWP2	1 interacting genes: GOLGA2
Entrez ID		54602	121642
HPRD ID		17629	14712
Ensembl ID		ENSG00000102471	ENSG00000189046
Uniprot IDs		B4DGY6 Q9NV92	Q6NS38
PDB IDs			3BTX 3BTY 3BTZ 3BU0 3BUC 3H8O 3H8R 3H8X 3RZG 3RZH 3RZJ 3RZK 3RZL 3RZM 3S57 3S5A 4MG2 4MGT
Enriched GO Terms of Interacting Partners?
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