ATP5PO and RCAN1

Data Source:
BioGRID (proximity labelling technology)

		ATP5PO	RCAN1
Description		ATP synthase peripheral stalk subunit OSCP	regulator of calcineurin 1
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrial Proton-transporting ATP Synthase, Stator Stalk Nucleus Mitochondrion Mitochondrial Inner Membrane Mitochondrial Proton-transporting ATP Synthase Complex Plasma Membrane Proton-transporting ATP Synthase Complex, Catalytic Core F(1)	Nucleus Cytoplasm
	Molecular Function	Protein Binding Proton-transporting ATP Synthase Activity, Rotational Mechanism	Nucleic Acid Binding Protein Binding Calcium-dependent Protein Serine/threonine Phosphatase Regulator Activity
	Biological Process	ATP Biosynthetic Process ATP Synthesis Coupled Proton Transport Cristae Formation Mitochondrial ATP Synthesis Coupled Proton Transport Proton Transmembrane Transport	Calcium-mediated Signaling Calcineurin-NFAT Signaling Cascade Regulation Of Phosphoprotein Phosphatase Activity Negative Regulation Of Calcineurin-NFAT Signaling Cascade
Pathways		Formation of ATP by chemiosmotic coupling Cristae formation
Drugs		Artenimol	Dipyridamole
Diseases
GWAS			Cancer ( 29299148) Rheumatoid arthritis ( 30423114 23143596 24390342) Rheumatoid arthritis (ACPA-positive) ( 23143596 24532676)
Interacting Genes		19 interacting genes: APP CCDC136 CEP70 ERCC6 GOLGA2 HMBOX1 KRT13 KRT15 MIPOL1 NDC80 NME6 NT5C2 PNMA1 TEX13A TFIP11 TRIP6 USHBP1 ZBTB14 ZNF76	8 interacting genes: APP BTRC GSK3B MAP3K3 MAPK3 PPP3CA USP22 UXT
Entrez ID		539	1827
HPRD ID		02899	04226
Ensembl ID		ENSG00000241837	ENSG00000159200
Uniprot IDs		P48047	B7Z1F0 E9PDJ2 P53805 Q6FGP2 Q6ZMM3 V9GYW9
PDB IDs			6UUQ
Enriched GO Terms of Interacting Partners?
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