ATP6AP1 and LARP1

Data Source:
BioGRID (affinity chromatography technology)

		ATP6AP1	LARP1
Description		ATPase H+ transporting accessory protein 1	La ribonucleoprotein 1, translational regulator
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Endosome Membrane Integral Component Of Membrane Proton-transporting Two-sector ATPase Complex Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Proton-transporting V-type ATPase, V1 Domain Plasma Membrane Proton-transporting V-type ATPase Complex Extracellular Exosome	Cytoplasm Polysome Cytoplasmic Stress Granule Membrane TORC1 Complex Polysomal Ribosome
	Molecular Function	Protein Binding ATP Binding Small GTPase Binding	RNA Cap Binding RNA 7-methylguanosine Cap Binding RNA Binding MRNA 3'-UTR Binding Protein Binding Eukaryotic Initiation Factor 4E Binding Translation Activator Activity Translation Initiation Factor Binding Ribosomal Small Subunit Binding Cadherin Binding MRNA 5'-UTR Binding
	Biological Process	Cellular Iron Ion Homeostasis Insulin Receptor Signaling Pathway Regulation Of Cellular PH Transferrin Transport Ion Transmembrane Transport Cellular Response To Increased Oxygen Levels Positive Regulation Of Osteoblast Differentiation Positive Regulation Of Bone Resorption PH Reduction Positive Regulation Of Exocytosis Establishment Of Organelle Localization Positive Regulation Of ERK1 And ERK2 Cascade Proton Transmembrane Transport Positive Regulation Of Osteoclast Development	Translational Initiation Cell Population Proliferation Posttranscriptional Regulation Of Gene Expression Positive Regulation Of Macroautophagy Negative Regulation Of Translation TOR Signaling TORC1 Signaling Positive Regulation Of Viral Genome Replication Negative Regulation Of Translational Initiation Positive Regulation Of Translational Initiation MRNA Stabilization Cellular Response To Rapamycin Response To Amino Acid Starvation
Pathways		Insulin receptor recycling Transferrin endocytosis and recycling Ion channel transport
Drugs		Tiludronic acid
Diseases
GWAS			Chin dimples ( 27182965) High light scatter reticulocyte percentage of red cells ( 32888494) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Monobrow ( 27182965) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		5 interacting genes: ANG ERBB2 HBA1 NR1I2 RHOU	9 interacting genes: BCL2L1 CSNK2A1 KASH5 SRPK1 TNNT1 YWHAB YWHAG YWHAQ YWHAZ
Entrez ID		537	23367
HPRD ID		02184	11225
Ensembl ID		ENSG00000071553	ENSG00000155506
Uniprot IDs		A0A0C4DGX8 A0A384MQW4 Q15904	Q6PKG0
PDB IDs			4ZC4 5C0V 5V4R 5V7C 5V87 6PW3
Enriched GO Terms of Interacting Partners?
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