PLS3 and TGIF2

Data Source:
BioGRID (pull down, affinity chromatography technology)

		PLS3	TGIF2
Description		plastin 3	TGFB induced factor homeobox 2
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Actin Filament Plasma Membrane Actin Filament Bundle	Chromatin Nucleus Nucleoplasm Centrosome
	Molecular Function	Calcium Ion Binding Actin Filament Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Sequence-specific Double-stranded DNA Binding
	Biological Process	Actin Filament Bundle Assembly Actin Filament Network Formation Bone Development	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Regulation Of Gastrulation Nodal Signaling Pathway Positive Regulation Of Neuron Differentiation Retina Development In Camera-type Eye
Pathways			Downregulation of SMAD2/3:SMAD4 transcriptional activity SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
Drugs
Diseases
GWAS		Gestational age at birth (maternal effect) ( 28877031) Mean platelet volume ( 32888494) Platelet count ( 32888494) Platelet distribution width ( 32888494) Preterm birth (maternal effect) ( 28877031)
Interacting Genes		2 interacting genes: APP ATXN2	5 interacting genes: FBXO7 HDAC1 RBBP8 SMAD3 TARBP2
Entrez ID		5358	60436
HPRD ID		02133	06293
Ensembl ID		ENSG00000102024	ENSG00000118707
Uniprot IDs		B4DPW9 P13797	Q9GZN2
PDB IDs		1AOA 1WJO
Enriched GO Terms of Interacting Partners?
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