PLOD1 and CD200

Data Source:
HPRD (in vivo)

		PLOD1	CD200
Description		procollagen-lysine,2-oxoglutarate 5-dioxygenase 1	CD200 molecule
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Rough Endoplasmic Reticulum Membrane Extracellular Exosome Catalytic Complex	Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Membrane Axon Neuron Projection Neuronal Cell Body Cell Body
	Molecular Function	Iron Ion Binding Protein Binding Procollagen-lysine 5-dioxygenase Activity L-ascorbic Acid Binding Procollagen Glucosyltransferase Activity	Protein Binding Protein Binding Involved In Heterotypic Cell-cell Adhesion Glycosylated Region Protein Binding
	Biological Process	Response To Hypoxia Protein O-linked Glycosylation Epidermis Development Peptidyl-lysine Hydroxylation Protein Phosphopantetheinylation	Negative Regulation Of Leukocyte Activation Negative Regulation Of Cell Population Proliferation Negative Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Interleukin-6 Production Positive Regulation Of CREB Transcription Factor Activity Heterotypic Cell-cell Adhesion Negative Regulation Of Macrophage Activation Regulation Of Immune Response Positive Regulation Of Transforming Growth Factor Beta Production Cell-cell Adhesion Positive Regulation Of Arginase Activity Positive Regulation Of Protein-glutamine Gamma-glutamyltransferase Activity Regulation Of Neuroinflammatory Response Negative Regulation Of Neuroinflammatory Response Negative Regulation Of Neuron Death Negative Regulation Of Matrix Metallopeptidase Secretion Negative Regulation Of Macrophage Migration Negative Regulation Of T Cell Migration
Pathways		Collagen biosynthesis and modifying enzymes	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs		Ascorbic acid
Diseases		Ehlers-Danlos syndrome (EDS), including: EDS classical type (EDS1/2); EDS hypermobility type (EDS3); EDS vascular type (EDS4); EDS kyphoscoliosis type (EDS6); EDS arthrochalasia type (EDS7A/7B); EDS dermatospraxis type (EDS7C); EDS autosomal recessive cardiac valvular form (EDSCV); EDS musculocontractural type (EDSMC); EDS progeroid form (EDSP); Tenascin-X deficiency (TNXD); Brittle cornea syndrome (EDS6B); EDS-like spondylocheiro dysplasia (SCD-EDS) Nevo syndrome
GWAS		Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962) Moyamoya disease ( 29273593) Platelet count ( 27863252) Plateletcrit ( 27863252) Tuberculosis ( 29036319)	Blood protein levels ( 30072576) Cognitive decline rate in late mild cognitive impairment ( 26252872) Eosinophil counts ( 32888494 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 32888494 27863252) Neutrophil percentage of granulocytes ( 27863252) Sum eosinophil basophil counts ( 27863252)
Interacting Genes		40 interacting genes: MIR1-2 MIR10B MIR122 MIR128-2 MIR141 MIR143 MIR15A MIR15B MIR17 MIR18A MIR18B MIR199A2 MIR19A MIR19B1 MIR206 MIR20A MIR214 MIR221 MIR222 MIR29B1 MIR34A MIR34B MIR363 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I USP4	3 interacting genes: CD200R1 HCRTR2 HUS1
Entrez ID		5351	4345
HPRD ID		01086	01124
Ensembl ID		ENSG00000083444	ENSG00000091972
Uniprot IDs		Q02809	B4DDZ6 F8W7G1 P41217
PDB IDs
Enriched GO Terms of Interacting Partners?
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