ZFYVE1 and PRKCH

Data Source:
BioGRID (genetic interference)

		ZFYVE1	PRKCH
Description		zinc finger FYVE-type containing 1	protein kinase C eta
Image		No pdb structure
GO Annotations	Cellular Component	Phagophore Assembly Site Mitochondrion Autophagosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Golgi Stack Lipid Droplet Membrane Mitochondria-associated Endoplasmic Reticulum Membrane Perinuclear Region Of Cytoplasm Extrinsic Component Of Omegasome Membrane Omegasome	Cytoplasm Cytosol Plasma Membrane Extracellular Exosome
	Molecular Function	Protein Binding 1-phosphatidylinositol Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Zinc Ion Binding Phosphatidylinositol-3-phosphate Binding Phosphatidylinositol-3,4-bisphosphate Binding	Protein Serine/threonine Kinase Activity Protein Kinase C Activity Calcium-dependent Protein Kinase C Activity Protein Binding ATP Binding Enzyme Binding Metal Ion Binding
	Biological Process	Cellular Response To Starvation Negative Regulation Of Phosphatase Activity Macroautophagy Lipid Droplet Formation	Protein Phosphorylation Signal Transduction Positive Regulation Of Macrophage Derived Foam Cell Differentiation Peptidyl-serine Phosphorylation Platelet Activation Negative Regulation Of Glial Cell Apoptotic Process Intracellular Signal Transduction Positive Regulation Of Keratinocyte Differentiation Positive Regulation Of B Cell Receptor Signaling Pathway Positive Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of Glial Cell Proliferation Positive Regulation Of Protein Localization To Plasma Membrane Regulation Of Bicellular Tight Junction Assembly
Pathways			Effects of PIP2 hydrolysis G alpha (z) signalling events
Drugs
Diseases
GWAS		LDL cholesterol levels ( 32203549) Metabolite levels ( 23823483) Red blood cell count ( 32888494) Red cell distribution width ( 32888494) Refractive error ( 32231278) Resistance to Mycobacterium tuberculosis in HIV-positive individuals measured by a negative tuberculin skin test (continuous) ( 28628665)	Asthma ( 32296059) Height ( 28552196) Obesity (early onset extreme) ( 23563609) Reading and spelling ( 23738518) Rheumatoid arthritis ( 30423114 22446963 24390342) Word reading ( 23738518) Yeast infection ( 28928442)
Interacting Genes		3 interacting genes: APP BCL2L1 MAGOHB	12 interacting genes: BANP CDK2 FYN GSK3A ITGB2 NUMB PARD6A PPP1R14A PRKD1 PTPN11 SRC ZBTB8OS
Entrez ID		53349	5583
HPRD ID		12017	05669
Ensembl ID		ENSG00000165861	ENSG00000027075
Uniprot IDs		Q9HBF4	P24723
PDB IDs			2FK9 3TXO
Enriched GO Terms of Interacting Partners?
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