TM6SF1 and MFGE8

Data Source:
BioGRID (affinity chromatography technology)

		TM6SF1	MFGE8
Description		transmembrane 6 superfamily member 1	milk fat globule EGF and factor V/VIII domain containing
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Lysosomal Membrane Integral Component Of Membrane	Extracellular Region Extracellular Space Endoplasmic Reticulum Lumen External Side Of Plasma Membrane Membrane Extrinsic Component Of Plasma Membrane Collagen-containing Extracellular Matrix Extracellular Exosome Extracellular Vesicle
	Molecular Function	Molecular_function	Phosphatidylserine Binding Integrin Binding Extracellular Matrix Structural Constituent Phosphatidylethanolamine Binding
	Biological Process	Biological_process	Angiogenesis Phagocytosis, Recognition Phagocytosis, Engulfment Cell Adhesion Single Fertilization Apoptotic Cell Clearance Post-translational Protein Modification Cellular Protein Metabolic Process Positive Regulation Of Phagocytosis
Pathways			Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation Amyloid fiber formation
Drugs
Diseases
GWAS		Diastolic blood pressure ( 27841878) Lymphocyte counts ( 32888494) Monocyte count ( 32888494)	Blood protein levels ( 30072576 29875488 28240269) Coronary artery disease ( 32469254 26343387 33020668) Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975) Height ( 31562340) Pulse pressure ( 27841878) Squamous cell lung carcinoma ( 28604730)
Interacting Genes		2 interacting genes: MFF PEX5
Entrez ID		53346	4240
HPRD ID		08411	03789
Ensembl ID		ENSG00000136404	ENSG00000140545
Uniprot IDs		Q6P4D7 Q9BZW5	B3KTQ2 B4E396 Q08431
PDB IDs
Enriched GO Terms of Interacting Partners?
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