PHKB and RICTOR

Data Source:
BioGRID (affinity chromatography technology)

		PHKB	RICTOR
Description		phosphorylase kinase regulatory subunit beta	RPTOR independent companion of MTOR complex 2
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane Phosphorylase Kinase Complex	Cytosol TORC2 Complex
	Molecular Function	Protein Binding Calmodulin Binding	Protein Binding Protein Kinase Binding Ribosome Binding Protein Serine/threonine Kinase Activator Activity
	Biological Process	Glycogen Metabolic Process Glycogen Catabolic Process Generation Of Precursor Metabolites And Energy Protein Phosphorylation	Positive Regulation Of Endothelial Cell Proliferation Embryo Development Ending In Birth Or Egg Hatching Regulation Of Gene Expression Viral Process Peptidyl-serine Phosphorylation Positive Regulation Of Actin Filament Polymerization Actin Cytoskeleton Reorganization Positive Regulation Of TOR Signaling Activation Of Protein Kinase B Activity Regulation Of Actin Cytoskeleton Organization Regulation Of Peptidyl-serine Phosphorylation TORC2 Signaling Regulation Of GTPase Activity Regulation Of Inflammatory Response Positive Regulation Of Peptidyl-tyrosine Phosphorylation Regulation Of Protein Kinase B Signaling Positive Regulation Of Protein Kinase B Signaling Positive Regulation Of Protein Serine/threonine Kinase Activity Regulation Of Establishment Of Cell Polarity
Pathways		Glycogen breakdown (glycogenolysis) Glycogen breakdown (glycogenolysis)	PIP3 activates AKT signaling CD28 dependent PI3K/Akt signaling VEGFR2 mediated vascular permeability Constitutive Signaling by AKT1 E17K in Cancer Regulation of TP53 Degradation
Drugs
Diseases		Glycogen storage diseases (GSD), including: von Gierke disease (GSD type Ia); Pompe disease (GSD type II); Cori disease, Forbe disease (GSD type III); Andersen disease (GSD type IV); McArdle disease (GSD type V); Hers disease (GSD type VI); Tarui disease (GSD type VII); Phosphorylase kinase deficiency (GSD type IX); Fanconi-Bickel syndrome (GSD type XI); Glycogen synthase deficiency (GSD type 0)
GWAS			Daytime sleep phenotypes ( 27126917) Immature fraction of reticulocytes ( 32888494) Obesity-related traits ( 23251661) Post bronchodilator FEV1 ( 26634245) Red blood cell count ( 32888494)
Interacting Genes		5 interacting genes: C20orf27 CALM1 CAMK2B HNRNPC PHKA2	11 interacting genes: CHUK CUL1 EIF4EBP1 GSK3A GSK3B IKBKB ILK MTOR PLK1 SGK1 SIRT1
Entrez ID		5257	253260
HPRD ID		01407	10682
Ensembl ID		ENSG00000102893	ENSG00000164327
Uniprot IDs		Q93100	Q6R327
PDB IDs			5ZCS
Enriched GO Terms of Interacting Partners?
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