ATP6V1A and GON4L

Data Source:
BioGRID (affinity chromatography technology)

		ATP6V1A	GON4L
Description		ATPase H+ transporting V1 subunit A	gon-4 like
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Lysosomal Membrane Cytosol Plasma Membrane Microvillus Apical Plasma Membrane Proton-transporting Two-sector ATPase Complex Proton-transporting V-type ATPase, V1 Domain Intracellular Membrane-bounded Organelle Extracellular Exosome	Nucleus Nucleoplasm Nuclear Body
	Molecular Function	ATP Binding ATPase Activity Proton-transporting ATP Synthase Activity, Rotational Mechanism Proton-transporting ATPase Activity, Rotational Mechanism	Transcription Coregulator Activity Transcription Corepressor Activity
	Biological Process	Cellular Iron Ion Homeostasis Insulin Receptor Signaling Pathway ATP Synthesis Coupled Proton Transport Regulation Of Macroautophagy Transferrin Transport Ion Transmembrane Transport Cellular Response To Increased Oxygen Levels Phagosome Acidification Proton Transmembrane Transport	Regulation Of Transcription, DNA-templated B Cell Differentiation Negative Regulation Of Transcription, DNA-templated
Pathways		ROS and RNS production in phagocytes Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport
Drugs		Alendronic acid Etidronic acid Tiludronic acid Bafilomycin A1 Bafilomycin B1
Diseases
GWAS		Prostate cancer ( 23535732)	Blood urea nitrogen levels ( 31152163) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body mass index ( 28892062) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Lewy body disease ( 25188341) Neuritic plaque ( 31497858) Periventricular white matter hyperintensities ( 32517579) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Urate levels ( 31578528)
Interacting Genes		6 interacting genes: ANXA7 CDC42 CDKN1A SMN1 TK1 TUFM	1 interacting genes: ITGB5
Entrez ID		523	54856
HPRD ID		06120	13370
Ensembl ID		ENSG00000114573	ENSG00000116580
Uniprot IDs		P38606	A4PB67 A4PB68 Q14BN2 Q3T8J9 Q9H986
PDB IDs
Enriched GO Terms of Interacting Partners?
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