ATP6V1A and LSAMP

Data Source:
BioGRID (proximity labelling technology)

		ATP6V1A	LSAMP
Description		ATPase H+ transporting V1 subunit A	limbic system associated membrane protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Lysosomal Membrane Cytosol Plasma Membrane Microvillus Apical Plasma Membrane Proton-transporting Two-sector ATPase Complex Proton-transporting V-type ATPase, V1 Domain Intracellular Membrane-bounded Organelle Extracellular Exosome	Extracellular Region Cytosol Plasma Membrane Anchored Component Of Membrane
	Molecular Function	ATP Binding ATPase Activity Proton-transporting ATP Synthase Activity, Rotational Mechanism Proton-transporting ATPase Activity, Rotational Mechanism	Protein Binding
	Biological Process	Cellular Iron Ion Homeostasis Insulin Receptor Signaling Pathway ATP Synthesis Coupled Proton Transport Regulation Of Macroautophagy Transferrin Transport Ion Transmembrane Transport Cellular Response To Increased Oxygen Levels Phagosome Acidification Proton Transmembrane Transport	Cell Adhesion Nervous System Development
Pathways		ROS and RNS production in phagocytes Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport	Post-translational modification: synthesis of GPI-anchored proteins
Drugs		Alendronic acid Etidronic acid Tiludronic acid Bafilomycin A1 Bafilomycin B1
Diseases
GWAS		Prostate cancer ( 23535732)	Blood protein levels ( 30072576 29875488) Chronotype ( 30696823) Colorectal or endometrial cancer ( 26621817) Emphysema imaging phenotypes ( 26030696) Experiencing mood swings ( 29500382) Feeling miserable ( 29500382) Fish- and plant-related diet ( 32066663) General factor of neuroticism ( 30867560) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Hip circumference ( 28552196) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Systemising ( 31508503) Tourette's syndrome or obsessive-compulsive disorder ( 25158072)
Interacting Genes		6 interacting genes: ANXA7 CDC42 CDKN1A SMN1 TK1 TUFM	3 interacting genes: NEGR1 NTM PRNP
Entrez ID		523	4045
HPRD ID		06120	09128
Ensembl ID		ENSG00000114573	ENSG00000185565
Uniprot IDs		P38606	B7Z661 Q13449
PDB IDs
Enriched GO Terms of Interacting Partners?
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