ATP6V1A and RALGAPA1

Data Source:
BioGRID (affinity chromatography technology)

		ATP6V1A	RALGAPA1
Description		ATPase H+ transporting V1 subunit A	Ral GTPase activating protein catalytic subunit alpha 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Lysosomal Membrane Cytosol Plasma Membrane Microvillus Apical Plasma Membrane Proton-transporting Two-sector ATPase Complex Proton-transporting V-type ATPase, V1 Domain Intracellular Membrane-bounded Organelle Extracellular Exosome	Nucleus Cytoplasm
	Molecular Function	ATP Binding ATPase Activity Proton-transporting ATP Synthase Activity, Rotational Mechanism Proton-transporting ATPase Activity, Rotational Mechanism	GTPase Activator Activity Protein Heterodimerization Activity
	Biological Process	Cellular Iron Ion Homeostasis Insulin Receptor Signaling Pathway ATP Synthesis Coupled Proton Transport Regulation Of Macroautophagy Transferrin Transport Ion Transmembrane Transport Cellular Response To Increased Oxygen Levels Phagosome Acidification Proton Transmembrane Transport	Regulation Of Small GTPase Mediated Signal Transduction Activation Of GTPase Activity
Pathways		ROS and RNS production in phagocytes Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport
Drugs		Alendronic acid Etidronic acid Tiludronic acid Bafilomycin A1 Bafilomycin B1
Diseases
GWAS		Prostate cancer ( 23535732)	Hematocrit ( 32888494) Hemoglobin ( 32888494) Red blood cell count ( 32888494)
Interacting Genes		6 interacting genes: ANXA7 CDC42 CDKN1A SMN1 TK1 TUFM	2 interacting genes: ERBB3 TCF3
Entrez ID		523	253959
HPRD ID		06120	12324
Ensembl ID		ENSG00000114573	ENSG00000174373
Uniprot IDs		P38606	A0A1B0GUI1 Q6GYQ0
PDB IDs
Enriched GO Terms of Interacting Partners?
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