CAB39 and GIGYF2

Data Source:
BioGRID (biochemical)

		CAB39	GIGYF2
Description		calcium binding protein 39	GRB10 interacting GYF protein 2
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GO Annotations	Cellular Component	Extracellular Region Cytosol Membrane Z Disc Secretory Granule Lumen Extracellular Exosome Serine/threonine Protein Kinase Complex Ficolin-1-rich Granule Lumen	Endosome Endoplasmic Reticulum Golgi Apparatus Cytosol Cytoplasmic Stress Granule Membrane Protein-containing Complex Perikaryon Proximal Dendrite
	Molecular Function	Protein Binding Kinase Binding Protein Kinase Activator Activity Protein Serine/threonine Kinase Activator Activity	RNA Binding Protein Binding Cadherin Binding Proline-rich Region Binding
	Biological Process	Cell Cycle Arrest Signal Transduction Positive Regulation Of Peptidyl-threonine Phosphorylation Response To Activity Peptidyl-serine Phosphorylation Activation Of Protein Kinase Activity Intracellular Signal Transduction Neutrophil Degranulation Cellular Hypotonic Response Positive Regulation Of Protein Serine/threonine Kinase Activity Response To Thyroid Hormone Negative Regulation Of Potassium Ion Transmembrane Transporter Activity Negative Regulation Of Potassium Ion Transmembrane Transport	Posttranscriptional Gene Silencing Negative Regulation Of Translation Insulin-like Growth Factor Receptor Signaling Pathway MRNA Destabilization
Pathways		Energy dependent regulation of mTOR by LKB1-AMPK Neutrophil degranulation
Drugs
Diseases			Parkinson's disease (PD)
GWAS			Anxiety and stress-related disorders ( 31116379) Autism spectrum disorder or schizophrenia ( 28540026) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Coronary artery disease ( 32469254 29212778 33020668) Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975) Schizophrenia ( 25056061 29483656 23974872)
Interacting Genes		12 interacting genes: CEP44 GOLGA2 IPO5 MCCD1 MED7 PRKAA1 RSL1D1 SHMT2 STK11 STK24 STRADA STRADB	8 interacting genes: APC CNOT9 GRB10 GRB14 GRB7 RBM12 SNRPB WBP11
Entrez ID		51719	26058
HPRD ID		10091	11639
Ensembl ID		ENSG00000135932	ENSG00000204120
Uniprot IDs		A0A024R496 Q9Y376	Q6Y7W6
PDB IDs		1UPK 1UPL 2WTK 3GNI 4FZA 4FZD 4FZF 4NZW 4O27	5NVL 5NVM
Enriched GO Terms of Interacting Partners?
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