PCP4 and GZMA

Data Source:
BioGRID (biochemical)

		PCP4	GZMA
Description		Purkinje cell protein 4	granzyme A
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GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Protein-containing Complex	Immunological Synapse Extracellular Region Nucleus
	Molecular Function	Calcium Ion Binding Protein Binding Calmodulin Binding	Serine-type Endopeptidase Activity Protein Binding Protein Homodimerization Activity
	Biological Process	Positive Regulation Of Neuron Differentiation Calmodulin Dependent Kinase Signaling Pathway	Apoptotic Process Immune Response Response To Bacterium Cytolysis Negative Regulation Of Endodeoxyribonuclease Activity Positive Regulation Of Apoptotic Process Negative Regulation Of DNA Binding Negative Regulation Of Oxidoreductase Activity Proteolysis Involved In Cellular Protein Catabolic Process Pyroptosis Granzyme-mediated Programmed Cell Death Signaling Pathway Cytotoxic T Cell Pyroptotic Process
Pathways
Drugs
Diseases
GWAS		Asthma ( 32296059) Metabolite levels ( 23823483) Systolic blood pressure (alcohol consumption interaction) ( 24376456) Venlafaxine response in generalised anxiety disorder (responders vs non-responders after 12 weeks) ( 28437668)
Interacting Genes		6 interacting genes: CALM1 CALML6 DAPK1 POT1 TERF1 TERF2IP	17 interacting genes: ACTG1 APEX1 GOLGA2 H1-1 H2BC21 HDC HMGB2 HNRNPK HSP90AA1 HSPA4 LMNA LMNB1 NCL NDUFS3 SET XRCC5 XRCC6
Entrez ID		5121	3001
HPRD ID		03378	00771
Ensembl ID		ENSG00000183036	ENSG00000145649
Uniprot IDs		P48539	P12544
PDB IDs		2N77	1HF1 1OP8 1ORF
Enriched GO Terms of Interacting Partners?
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